关键词: Dimorphic fungi Emergomyces Emergomycosis Emmonsia Endemic mycoses Mycosis Skin infection

Mesh : Humans Mycoses / microbiology HIV Infections

来  源:   DOI:10.1016/j.mycmed.2022.101313

Abstract:
Purpose of Review In this review, we provide an overview of emergomycosis from a clinical perspective and discuss the taxonomy and classification of the pathogens, epidemiology, pathophysiology of infection and mechanisms of pathogenesis, immunology, clinical manifestations, laboratory culture and diagnosis, molecular characterisation, therapy and prognosis. Recent Findings While Emergomyces pasteurianus is the most geographically-widespread species, Emergomyces africanus is endemic to Southern Africa and causes disseminated disease with cutaneous involvement primarily among patients with advanced human immunodeficiency virus (HIV) disease. Summary Emergomycosis, a disseminated clinical disease resulting from infection with dimorphic fungi in the genus Emergomyces, occurs primarily among immunocompromised patients. Further knowledge is needed on the pathophysiology, diagnosis and management of emergomycosis.
摘要:
审查的目的在这篇审查中,我们从临床角度提供了一个概述,并讨论了分类和分类的病原体,流行病学,感染的病理生理学和发病机制,免疫学,临床表现,实验室培养和诊断,分子表征,治疗和预后。最近的研究结果虽然巴斯德氏菌是地理上分布最广泛的物种,非洲雏菊是南部非洲的地方病,主要在晚期人类免疫缺陷病毒(HIV)疾病患者中引起皮肤累及的播散性疾病。总结出毛菌病,一种传播的临床疾病,是由于感染了Emergomyces属的双态真菌而引起的,主要发生在免疫功能低下的患者中。需要进一步了解病理生理学,真菌病的诊断和治疗。
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