Abstract：
Central nervous system germ cell tumors (CNSGCTs) are rare neoplasms which usually develop in the midline structures. They are occasionally involved in off-midline structures of the brain. Here, we report an extremely rare case of an intracranial germinoma in the lateral ventricle. The patient was a 10-year-old boy with a 1-year history of polydipsia and polyuria. Brain magnetic resonance imaging (MRI) showed a relatively homogeneously enhancing lesion in the lateral ventricle, and the posterior pituitary gland was not hyperintense on T1-weighted imaging. Subependymoma was suspected, and tumor removal operation was performed; however, because the intraoperative pathological investigation revealed germinoma, we could only perform partial removal of the tumor. Postoperative histology also confirmed germinoma. Then, the patient received chemotherapy, followed by radiation therapy. MRI showed no recurrence for 6 years after treatment. Intracranial germinoma in the lateral ventricle is extremely rare. The diagnosis is occasionally challenging, especially when the tumors are located in atypical locations. This paper presents a literature review of previously described CNSGCTs of the lateral ventricle to improve awareness of CNSGCTs in atypical locations. We also consider the relationship between imaging findings and clinical manifestations.
摘要：
中枢神经系统生殖细胞肿瘤（CNSGCT）是罕见的肿瘤，通常在中线结构中发展。他们偶尔参与大脑的中线结构。这里,我们报道了一例极为罕见的侧脑室颅内生殖细胞瘤。患者为10岁男孩，有1年多饮和多尿病史。脑磁共振成像（MRI）显示侧脑室相对均匀增强的病变，在T1加权成像中，垂体后叶没有高信号。怀疑室管膜下瘤,进行了肿瘤切除手术；然而，因为术中病理检查显示生殖细胞瘤，我们只能部分切除肿瘤.术后组织学也证实生殖细胞瘤。然后，病人接受了化疗,其次是放射治疗。MRI显示治疗后6年无复发。侧脑室颅内生殖细胞瘤极为罕见。诊断偶尔具有挑战性，特别是当肿瘤位于非典型位置时。本文介绍了先前描述的侧脑室CNSGCT的文献综述，以提高对非典型位置CNSGCT的认识。我们还考虑了影像学表现与临床表现之间的关系。
