Abstract：
Voice change after uncomplicated thyroidectomy has been an important issue in the field of thyroid surgery. The aim of this study was to promote understanding of voice change after uncomplicated thyroidectomy by analysing the results for a large number of patients from a single institute.
We retrospectively reviewed the medical records of 2879 consecutive patients who underwent thyroidectomy and voice evaluation between January 2014 and December 2019 in a single institute. All the patients had their vocal status assessed using videostroboscopy, acoustic voice analyses, aerodynamic study, and Thyroidectomy-related Voice and Symptom Questionnaire (TVSQ) scores preoperatively and at 1, 3, and 6 months postoperatively. We analysed the pattern of voice changes over time and differences in voice parameters based on clinical factors. To confirm the usefulness of the TVSQ, the correlation between TVSQ scores and objective parameters was analysed. Lastly, predictive factors for persistent voice symptoms were analysed.
Tertiary referral hospital.
The frequency ranges and TVSQ scores exhibited significant deterioration until 6 months following surgery. Among clinical factors, the extents of thyroidectomy and neck dissection were associated with worse voice parameters. The TVSQ score was significantly correlated with objective voice parameters. The extents of thyroidectomy and neck dissection were predictive of persistent voice symptoms at 6 months after thyroidectomy.
After uncomplicated thyroidectomy, most voice parameters tended to recover, but some parameters remained aggravated even at 6 months after surgery. With more extensive surgery, worse voice quality and the higher risk of persistent voice symptoms may be anticipated.
We retrospectively reviewed the medical records of 2879 consecutive patients who underwent thyroidectomy and voice evaluation between January 2014 and December 2019 in a single institute. All the patients had their vocal status assessed using videostroboscopy, acoustic voice analyses, aerodynamic study, and Thyroidectomy-related Voice and Symptom Questionnaire (TVSQ) scores preoperatively and at 1, 3, and 6 months postoperatively. We analysed the pattern of voice changes over time and differences in voice parameters based on clinical factors. To confirm the usefulness of the TVSQ, the correlation between TVSQ scores and objective parameters was analysed. Lastly, predictive factors for persistent voice symptoms were analysed.
Tertiary referral hospital.
The frequency ranges and TVSQ scores exhibited significant deterioration until 6 months following surgery. Among clinical factors, the extents of thyroidectomy and neck dissection were associated with worse voice parameters. The TVSQ score was significantly correlated with objective voice parameters. The extents of thyroidectomy and neck dissection were predictive of persistent voice symptoms at 6 months after thyroidectomy.
After uncomplicated thyroidectomy, most voice parameters tended to recover, but some parameters remained aggravated even at 6 months after surgery. With more extensive surgery, worse voice quality and the higher risk of persistent voice symptoms may be anticipated.
摘要：
目的：单纯性甲状腺切除术后的语音变化一直是甲状腺外科领域的重要问题。这项研究的目的是通过分析单个研究所的大量患者的结果，促进对简单甲状腺切除术后声音变化的理解。
方法：我们回顾性回顾了2014年1月至2019年12月在一家机构接受甲状腺切除术和语音评估的2879例连续患者的医疗记录。所有患者都使用视光镜检查评估了他们的声音状态，声学语音分析，空气动力学研究,术前和术后1、3和6个月甲状腺切除术相关的语音和症状问卷（TVSQ）评分。我们根据临床因素分析了语音随时间的变化模式和语音参数的差异。为了证实TVSQ的有用性，分析了TVSQ评分与客观参数之间的相关性。最后,对持续性嗓音症状的预测因素进行了分析.
方法：三级转诊医院。
结果：直到手术后6个月，频率范围和TVSQ评分都表现出明显的恶化。在临床因素中，甲状腺切除术和颈清扫术的程度与较差的语音参数相关。TVSQ评分与客观语音参数显着相关。甲状腺切除术和颈清扫术的程度可预测甲状腺切除术后6个月的持续声音症状。
结论：在无并发症的甲状腺切除术后，大多数语音参数趋于恢复，但一些参数甚至在手术后6个月仍加重.随着更广泛的手术，可能预期语音质量较差,出现持续语音症状的风险较高.
方法：我们回顾性回顾了2014年1月至2019年12月在一家机构接受甲状腺切除术和语音评估的2879例连续患者的医疗记录。所有患者都使用视光镜检查评估了他们的声音状态，声学语音分析，空气动力学研究,术前和术后1、3和6个月甲状腺切除术相关的语音和症状问卷（TVSQ）评分。我们根据临床因素分析了语音随时间的变化模式和语音参数的差异。为了证实TVSQ的有用性，分析了TVSQ评分与客观参数之间的相关性。最后,对持续性嗓音症状的预测因素进行了分析.
方法：三级转诊医院。
结果：直到手术后6个月，频率范围和TVSQ评分都表现出明显的恶化。在临床因素中，甲状腺切除术和颈清扫术的程度与较差的语音参数相关。TVSQ评分与客观语音参数显着相关。甲状腺切除术和颈清扫术的程度可预测甲状腺切除术后6个月的持续声音症状。
结论：在无并发症的甲状腺切除术后，大多数语音参数趋于恢复，但一些参数甚至在手术后6个月仍加重.随着更广泛的手术，可能预期语音质量较差,出现持续语音症状的风险较高.
