PDF(Pubmed)
Abstract：
UNASSIGNED: Diagnosing bullous eruptions in systemic lupus erythematosus (SLE) patients is challenging because there are so many differential diagnoses, including drug reactions such as Stevens-Johnson syndrome (SJS)/toxic epidermal necrolysis (TEN) and TEN-like cutaneous lupus erythematosus (LE).
UNASSIGNED: An Indonesian female with a SLE history complained of an erythematous rash over the body 2 weeks ago. A pulse dose of methylprednisolone was given, and after 3 days, of getting bullae appeared all over the body and treatment stopped. The patient is treated in collaboration with dermatology, ophthalmology, and allergy consultants to obtain a diagnosis of SJS supporting skin biopsy. The patient was given methylprednisolone 62.5 mg once daily for 7 days, Gentamicin 80 mg twice daily, and the skin lesion was treated with NaCl 0.9% compression. The patient showed improvement and decreased methylprednisolone dose to 16 mg 3 times a day.
UNASSIGNED: Skin biopsy must be obtained to establish the diagnosis between JSJ/TEN and cutaneous LE.
UNASSIGNED: SJS/TEN can occur in SLE patients. The correct diagnosis can reduce the patient\'s mortality and morbidity.
UNASSIGNED: An Indonesian female with a SLE history complained of an erythematous rash over the body 2 weeks ago. A pulse dose of methylprednisolone was given, and after 3 days, of getting bullae appeared all over the body and treatment stopped. The patient is treated in collaboration with dermatology, ophthalmology, and allergy consultants to obtain a diagnosis of SJS supporting skin biopsy. The patient was given methylprednisolone 62.5 mg once daily for 7 days, Gentamicin 80 mg twice daily, and the skin lesion was treated with NaCl 0.9% compression. The patient showed improvement and decreased methylprednisolone dose to 16 mg 3 times a day.
UNASSIGNED: Skin biopsy must be obtained to establish the diagnosis between JSJ/TEN and cutaneous LE.
UNASSIGNED: SJS/TEN can occur in SLE patients. The correct diagnosis can reduce the patient\'s mortality and morbidity.
摘要：
未经证实：诊断系统性红斑狼疮（SLE）患者的大疱性皮疹具有挑战性，因为有很多鉴别诊断，包括Stevens-Johnson综合征（SJS）/中毒性表皮坏死松解症（TEN）和TEN样皮肤红斑狼疮（LE）等药物反应。
未经证实：一名有SLE病史的印尼女性在2周前抱怨身体出现红斑皮疹。给予甲基强的松龙的脉冲剂量，3天后,大疱出现在全身，治疗停止了。患者与皮肤科合作治疗，眼科,和过敏顾问获得SJS诊断支持皮肤活检。患者给予甲泼尼龙62.5mg，每日一次，连续7天，庆大霉素80毫克，每日两次，皮肤病变用0.9%NaCl压迫治疗。患者表现出改善和减少甲基强的松龙剂量至16mg每天3次。
UNASSIGNED：必须进行皮肤活检才能确定JSJ/TEN与皮肤LE之间的诊断。
未经证实：SJS/TEN可发生在SLE患者中。正确的诊断可以降低患者的死亡率和发病率。
未经证实：一名有SLE病史的印尼女性在2周前抱怨身体出现红斑皮疹。给予甲基强的松龙的脉冲剂量，3天后,大疱出现在全身，治疗停止了。患者与皮肤科合作治疗，眼科,和过敏顾问获得SJS诊断支持皮肤活检。患者给予甲泼尼龙62.5mg，每日一次，连续7天，庆大霉素80毫克，每日两次，皮肤病变用0.9%NaCl压迫治疗。患者表现出改善和减少甲基强的松龙剂量至16mg每天3次。
UNASSIGNED：必须进行皮肤活检才能确定JSJ/TEN与皮肤LE之间的诊断。
未经证实：SJS/TEN可发生在SLE患者中。正确的诊断可以降低患者的死亡率和发病率。
