PDF(Pubmed)
Abstract：
Digital workflow transformation continues to sweep throughout a diversity of pathology departments spanning the globe following catalyzation of whole slide imaging (WSI) adoption by the SARS-CoV-2 (COVID-19) pandemic. The utility of WSI for a litany of use cases including primary diagnosis has been emphasized during this period, with WSI scanning devices gaining the approval of healthcare regulatory bodies and practitioners alike for clinical applications following extensive validatory efforts. As successful validation for WSI is predicated upon pathologist diagnostic interpretability of digital images with high glass slide concordance, departmental adoption of WSI is tantamount to the reliability of such images often predicated upon quality assessment notwithstanding image interpretability but extending to quality of practice following WSI adoption. Metrics of importance within this context include failure rates inclusive of different scanning errors that result in poor image quality and the potential such errors may incur upon departmental turnaround time (TAT). We sought to evaluate the impact of WSI implementation through retrospective evaluation of scan failure frequency in archival versus newly prepared slides, types of scanning error, and impact upon TAT following commencement of live WSI operation in May 2017 until the present period within a fully digitized high-volume academic institution. A 1.19% scan failure incidence rate was recorded during this period, with re-scanning requested and successfully executed for 1.19% of cases during the reported period of January 2019 until present. No significant impact upon TAT was deduced, suggesting an outcome which may be encouraging for departments considering digital workflow adoption.
摘要：
在SARS-CoV-2（COVID-19）大流行催化采用全载玻片成像（WSI）之后，数字工作流程转换继续席卷全球多种病理部门。在此期间，强调了WSI在一系列用例中的实用性，包括初级诊断，WSI扫描设备在经过广泛的验证工作后，获得了医疗保健监管机构和从业人员的临床应用批准。由于WSI的成功验证是基于病理学家对具有高载玻片一致性的数字图像的诊断可解释性，部门采用WSI等于此类图像的可靠性，通常取决于质量评估，尽管图像具有可解释性，但在采用WSI后扩展到实践质量。在该上下文中的重要性度量包括故障率,包括导致差的图像质量的不同扫描错误,并且潜在的这种错误可能在部门周转时间(TAT)时招致。我们试图通过回顾性评估归档与新准备的幻灯片中的扫描失败频率来评估WSI实施的影响。扫描错误的类型，以及在2017年5月开始实时WSI运营后对TAT的影响，直到目前在一个完全数字化的高容量学术机构内。在此期间记录了1.19%的扫描失败发生率，在2019年1月至今的报告期内，1.19%的病例被请求重新扫描并成功执行。对TAT没有重大影响，建议一个结果，这对于考虑采用数字工作流程的部门来说可能是令人鼓舞的。
