This review was performed following the 2020 Preferred Reporting Items for Systematic Reviews and Meta-Analyses framework. Continuous variables were analyzed using the inverse variance of the mean difference with a random effect, 95% confidence interval (CI), and p-value. The incidence of complications, unacceptable appearance, and reoperation rate were pooled using the Cochran-Mantel-Haenszel Method with the random effect model and reported as odds ratio (OR), 95% CI, and p-value. Significance was set at p-value ≤0.05 and 95%CI.
Seven studies were included. In comparison to the conventional circumcision, laser circumcision shoved lower visual analogue score at 24-h, and 7 days after surgery, a lower rate of overall complication rate (OR 0.33, 95% CI 0.24-0.47, p < 0.001), scarring (OR 0.09, 95% CI 0.02, 0.41, p = 0.002), and unacceptable appearance (OR 0.09, 95% CI 0.05, 0.15, p < 0.001). We found no statistically significant difference in surgical time, and incidence of bleeding, infection, wound dehiscence, and reoperation rate.
Our review infers that laser-assisted circumcision is certainly a safe and strong contender as the procedure of choice in both children and adult populations.
方法:本综述遵循2020年首选报告项目的系统评价和荟萃分析框架。连续变量使用具有随机效应的平均差的逆方差分析,95%置信区间(CI),和p值。并发症的发生率,不可接受的外观,使用Cochran-Mantel-Haenszel方法与随机效应模型合并再手术率,并报告为比值比(OR),95%CI和p值。显著性设定为p值≤0.05和95CI。
结果:纳入7项研究。与传统包皮环切术相比,激光包皮环切术在24小时降低了视觉模拟评分,手术后7天,总体并发症发生率较低(OR0.33,95%CI0.24-0.47,p<0.001),瘢痕形成(OR0.09,95%CI0.02,0.41,p=0.002),和不可接受的外观(OR0.09,95%CI0.05,0.15,p<0.001)。我们发现手术时间无统计学差异,和出血的发生率,感染,伤口裂开,和再手术率。
结论:我们的评论推断,激光辅助包皮环切术作为儿童和成人人群的首选手术,无疑是一种安全且有力的有力有力的有力有力有力的选择。