PDF(Pubmed)
Abstract：
UNASSIGNED: To develop a method to determine the volume of peripapillary hyperreflective ovoid masslike structures (PHOMS) and to examine the correlation between PHOMS and anatomic optic nerve head characteristics in a large cohort of patients with optic disc drusen (ODD).
UNASSIGNED: Retrospective, observational study of patients with ODD.
UNASSIGNED: Patients with ODD seen in a 3-year period.
UNASSIGNED: We determined the prevalence of PHOMS. We then developed a method to calculate the volume of PHOMS and measured this in all patients where radial scans on OCT were available. We analyzed the correlation between PHOMS volume and patient age, size of Bruch\'s membrane opening (BMO), ODD visibility, and anatomic location of ODD in the optic nerve.
UNASSIGNED: Prevalence and characteristics of PHOMS in patients with ODD.
UNASSIGNED: In 247 (77%) eyes with ODD, PHOMS were found. Among these, 80% were in the first decade of life, 87% were in the second decade, 89% were in the third decade, 85% were in the fourth decade, 74% were in the fifth decade, 73% were in the sixth decade, 58% were in the seventh decade, 40% were in the eighth decade, and 0% were in the ninth decade. The ophthalmoscopic visibility of ODD increased with age. The volume of PHOMS decreased with age, but with no correlation to the size of BMO. The median volume of PHOMS was 0.27 mm3 (interquartile range [IQR], 0.13-0.49 mm3). Predominantly, PHOMS were observed in the nasal peripapillary area (87.5% nasal, 78.5% superior, 67% inferior, and 63.5% temporal).
UNASSIGNED: In patients with ODD, PHOMS are seen frequently, with the highest prevalence in younger individuals. The volume of PHOMS decreases with age, and PHOMS are seen more frequently in patients with superficial ODD.
UNASSIGNED: Retrospective, observational study of patients with ODD.
UNASSIGNED: Patients with ODD seen in a 3-year period.
UNASSIGNED: We determined the prevalence of PHOMS. We then developed a method to calculate the volume of PHOMS and measured this in all patients where radial scans on OCT were available. We analyzed the correlation between PHOMS volume and patient age, size of Bruch\'s membrane opening (BMO), ODD visibility, and anatomic location of ODD in the optic nerve.
UNASSIGNED: Prevalence and characteristics of PHOMS in patients with ODD.
UNASSIGNED: In 247 (77%) eyes with ODD, PHOMS were found. Among these, 80% were in the first decade of life, 87% were in the second decade, 89% were in the third decade, 85% were in the fourth decade, 74% were in the fifth decade, 73% were in the sixth decade, 58% were in the seventh decade, 40% were in the eighth decade, and 0% were in the ninth decade. The ophthalmoscopic visibility of ODD increased with age. The volume of PHOMS decreased with age, but with no correlation to the size of BMO. The median volume of PHOMS was 0.27 mm3 (interquartile range [IQR], 0.13-0.49 mm3). Predominantly, PHOMS were observed in the nasal peripapillary area (87.5% nasal, 78.5% superior, 67% inferior, and 63.5% temporal).
UNASSIGNED: In patients with ODD, PHOMS are seen frequently, with the highest prevalence in younger individuals. The volume of PHOMS decreases with age, and PHOMS are seen more frequently in patients with superficial ODD.
摘要：
UNASSIGNED：开发一种方法来确定视盘玻璃疣（ODD）患者的乳头周围高反射卵形块状结构（PHOMS）的体积，并检查PHOMS与解剖性视神经乳头特征之间的相关性。
未经批准：回顾性，ODD患者的观察性研究。
未经证实：在3年内观察到的ODD患者。
未经授权：我们确定了PHOMS的患病率。然后，我们开发了一种计算PHOMS体积的方法，并在所有可进行OCT径向扫描的患者中进行了测量。我们分析了PHOMS体积与患者年龄之间的相关性，布鲁赫膜开口(BMO)的尺寸，ODD可见性,以及ODD在视神经中的解剖位置。
未经证实：ODD患者PHOMS的患病率和特征。
未经评估：在247只（77％）具有ODD的眼睛中，找到了PHOMS。其中,80%是在生命的第一个十年，87%是在第二个十年，89%是在第三个十年，85%是在第四个十年，74%的人在第五个十年，73%的人在第六个十年，58%是在第七个十年，40%是在第八个十年，0%在第九个十年。ODD的检眼镜能见度随年龄增长而增加。PHOMS的体积随着年龄的增长而减少，但与BMO的大小无关。PHOMS的中值体积为0.27mm3(四分位距[IQR]，0.13-0.49mm3)。主要是,在鼻乳头周围区域观察到PHOMS（87.5％的鼻，78.5%优,67%劣质，和63.5%时间)。
未经批准：在ODD患者中，经常看到PHOMS,在年轻人中患病率最高。PHOMS的体积随着年龄的增长而减少，和PHOMS在浅表ODD患者中更常见。
未经批准：回顾性，ODD患者的观察性研究。
未经证实：在3年内观察到的ODD患者。
未经授权：我们确定了PHOMS的患病率。然后，我们开发了一种计算PHOMS体积的方法，并在所有可进行OCT径向扫描的患者中进行了测量。我们分析了PHOMS体积与患者年龄之间的相关性，布鲁赫膜开口(BMO)的尺寸，ODD可见性,以及ODD在视神经中的解剖位置。
未经证实：ODD患者PHOMS的患病率和特征。
未经评估：在247只（77％）具有ODD的眼睛中，找到了PHOMS。其中,80%是在生命的第一个十年，87%是在第二个十年，89%是在第三个十年，85%是在第四个十年，74%的人在第五个十年，73%的人在第六个十年，58%是在第七个十年，40%是在第八个十年，0%在第九个十年。ODD的检眼镜能见度随年龄增长而增加。PHOMS的体积随着年龄的增长而减少，但与BMO的大小无关。PHOMS的中值体积为0.27mm3(四分位距[IQR]，0.13-0.49mm3)。主要是,在鼻乳头周围区域观察到PHOMS（87.5％的鼻，78.5%优,67%劣质，和63.5%时间)。
未经批准：在ODD患者中，经常看到PHOMS,在年轻人中患病率最高。PHOMS的体积随着年龄的增长而减少，和PHOMS在浅表ODD患者中更常见。
