Mesh : Adult Female Giant Cells / pathology Histiocytoma, Benign Fibrous / pathology Humans Iron Melanins Skin Neoplasms / pathology Adult Female Giant Cells / pathology Histiocytoma, Benign Fibrous / pathology Humans Iron Melanins Skin Neoplasms / pathology

来  源:   DOI:10.1097/DAD.0000000000002309

Abstract:
UNASSIGNED: Multinucleate cell angiohistiocytoma (MCAH) is a benign vascular and fibrohistiocytic (probably reactive) proliferation with peculiar multinucleate cells which most authors interpret as degenerated macrophages. Several clinical variants of MCAH have been described, some of them with brownish-appearing lesions clinically. However, no histologically identified pigment has been described in the cytoplasm of the multinucleate cells so far. We present a pigmented MCAH with cytoplasmic brownish pigment, which was positive with a Masson-Fontana stain and negative with an iron stain, consistent with melanin, in a 33-year-old woman with multiple papules and plaques on the right elbow, right jawline, and left flank.
摘要:
未经证实:多核细胞血管间质细胞瘤(MCAH)是一种良性血管和纤维组织细胞(可能是反应性)增殖,具有特殊的多核细胞,大多数作者将其解释为退化的巨噬细胞。已经描述了MCAH的几种临床变体,其中一些临床上出现褐色病变。然而,到目前为止,在多核细胞的细胞质中还没有发现组织学上鉴定的色素。我们提出了一种具有细胞质褐色色素的色素MCAH,Masson-Fontana染色呈阳性,铁染色呈阴性,与黑色素一致,一名33岁的女性右肘有多处丘疹和斑块,右下颚线,和左翼。
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