关键词: asthma birth cohort study developmental delays eczema gastrointestinal disorders microbiota

来  源:   DOI:10.3389/fnut.2022.994607   PDF(Pubmed)

Abstract:
UNASSIGNED: The microbiota plays a key role in early immunity maturation that affects infant health and is associated with the development of non-communicable diseases and allergies in later life.
UNASSIGNED: The MYBIOTA is a prospective mother-infant cohort study in Malaysia aiming to determine the association between gut microbiota with infant health (temperament, gastrointestinal disorders, eczema, asthma, and developmental delays) in Selangor, Malaysia.
UNASSIGNED: Pregnant mothers will be enrolled in their first trimester of pregnancy, and follow-ups will be done for infants during their first year of life. Maternal-infant biological samples (blood, feces, saliva, urine, and breast milk), anthropometric, dietary, and clinical information will be collected at different time points from early pregnancy to 12 months postpartum.
UNASSIGNED: This study could provide a better understanding of the colonization and development of the gut microbiome during early life and its impact on infant health.
UNASSIGNED: https://clinicaltrials.gov/, identifier NCT04919265.
摘要:
微生物群在影响婴儿健康的早期免疫成熟中起着关键作用,并且与非传染性疾病和以后生活中过敏的发展有关。
MYBIOTA是马来西亚的一项前瞻性母婴队列研究,旨在确定肠道菌群与婴儿健康之间的关联(气质,胃肠道疾病,湿疹,哮喘,和发育迟缓)在雪兰戈尔,马来西亚。
怀孕的母亲将在怀孕的头三个月登记,将在婴儿出生后的第一年进行随访。母婴生物样本(血液,粪便,唾液,尿液,和母乳),人体测量学,饮食,和临床信息将在从妊娠早期到产后12个月的不同时间点收集。
这项研究可以更好地了解早期肠道微生物组的定植和发育及其对婴儿健康的影响。
https://clinicaltrials.gov/,标识符NCT04919265。
公众号