PDF(Pubmed)
Abstract：
UNASSIGNED: Drug-induced gingival overgrowth is associated with the intake of three classes of drugs: anticonvulsants, immunosuppressants, and calcium channel blockers. It is clinically characterized by hyperplasia of the gingival connective tissue which appears edematous, bloody, and purplish-red in color. In more severe cases, drug-induced gingival hyperplasia negatively affects the patient\'s quality of life, making it difficult to eat and practice good oral hygiene. Drug-induced gingival overgrowth therapy is controversial and, in fact, no studies in the literature highlight a well-defined therapeutic protocol. The therapies that are described provide primarily for non-surgical periodontal treatment and second-line surgical treatment. The aim of this work is to highlight a case of drug-induced gingival hyperplasia which was completely resolved thanks to photodynamic therapy which is completely free from side effects.
UNASSIGNED: Photodynamic therapy was performed on an 18 year-old female patient with LEDs at a power of 450-470 nm and 5500 mW/cm2 + 7500 mW/cm2, combined with a Curcuma longa-based photosensitizer. A single session was performed, with applications of approximately 30 s for each interdental papilla.
UNASSIGNED: The patient improved markedly after only one cycle of PDT. There was an absence of clinically detectable inflammation, edema, and rubor of the involved dental papillae. At the 4, 6, and 12 week follow-ups there were no recurrences.
UNASSIGNED: This case report highlights the first case of drug-induced gingival hypertrophy entirely treated with photodynamic therapy to be described in the literature. Therefore, although it is only a case report, this therapy which is free from side effects should be investigated as an alternative to current therapies.
UNASSIGNED: Photodynamic therapy was performed on an 18 year-old female patient with LEDs at a power of 450-470 nm and 5500 mW/cm2 + 7500 mW/cm2, combined with a Curcuma longa-based photosensitizer. A single session was performed, with applications of approximately 30 s for each interdental papilla.
UNASSIGNED: The patient improved markedly after only one cycle of PDT. There was an absence of clinically detectable inflammation, edema, and rubor of the involved dental papillae. At the 4, 6, and 12 week follow-ups there were no recurrences.
UNASSIGNED: This case report highlights the first case of drug-induced gingival hypertrophy entirely treated with photodynamic therapy to be described in the literature. Therefore, although it is only a case report, this therapy which is free from side effects should be investigated as an alternative to current therapies.
摘要：
未经批准：药物诱导的牙龈过度生长与三类药物的摄入有关：抗惊厥药，免疫抑制剂,和钙通道阻滞剂.它的临床特征是牙龈结缔组织增生，表现为水肿，血腥，和紫红色的颜色。在更严重的情况下，药物引起的牙龈增生会对患者的生活质量产生负面影响，很难进食和保持良好的口腔卫生。药物引起的牙龈过度生长疗法是有争议的,事实上,文献中没有研究强调明确的治疗方案.所描述的疗法主要提供非手术牙周治疗和二线手术治疗。这项工作的目的是强调一个由药物引起的牙龈增生的案例，由于光动力疗法完全没有副作用，该案例已完全解决。
UNASSIGNED：对一名18岁女性患者进行了光动力治疗，LED功率为450-470nm，功率为5500mW/cm2+7500mW/cm2，并结合了基于姜黄的光敏剂。进行了一次会话，每个牙间乳头应用约30s。
未经证实：患者仅接受一个周期的PDT治疗后明显改善。没有临床上可检测到的炎症，水肿,和牙齿乳头的光泽。在第4、6和12周的随访中，没有复发。
UNASSIGNED：本病例报告重点介绍了文献中描述的第一例完全用光动力疗法治疗的药物诱导的牙龈肥大。因此,虽然只是个案报告,这种没有副作用的疗法应作为现有疗法的替代方案进行研究。
UNASSIGNED：对一名18岁女性患者进行了光动力治疗，LED功率为450-470nm，功率为5500mW/cm2+7500mW/cm2，并结合了基于姜黄的光敏剂。进行了一次会话，每个牙间乳头应用约30s。
未经证实：患者仅接受一个周期的PDT治疗后明显改善。没有临床上可检测到的炎症，水肿,和牙齿乳头的光泽。在第4、6和12周的随访中，没有复发。
UNASSIGNED：本病例报告重点介绍了文献中描述的第一例完全用光动力疗法治疗的药物诱导的牙龈肥大。因此,虽然只是个案报告,这种没有副作用的疗法应作为现有疗法的替代方案进行研究。
