Abstract：
OBJECTIVE: We examined whether preoperative assessment of percentage of low attenuation area (LAA%) on the non-resected side can predict postoperative respiratory complications (PRC) after lobectomy.
METHODS: We conducted a historical cohort study of 217 smokers (175 males and 42 females) who underwent lobectomy for primary lung cancer at our hospital between January 2014 and March 2021. First, the relationship between LAA% and respiratory function parameters (RFPs) calculated for both the bilateral and non-resected sides was used to estimate the most effective patient group. Next, multivariate analyses of the relationship between LAA% of the non-resected side and PRC were performed using logistic regression analysis after adjusting for basic patient attributes and respiratory function.
RESULTS: A correlation was found between LAA% and RFP in smoking males. Multivariate analysis showed a strong relationship between model 3, adjusted for basic patient attributes and lung function factors, and PRC (odds ratio, 2.43; 95% confidence interval, 1.05-5.63).
CONCLUSIONS: LAA% of the non-resected side suggested that it may be able to predict the occurrence of PRC after lung cancer lobectomy.
METHODS: We conducted a historical cohort study of 217 smokers (175 males and 42 females) who underwent lobectomy for primary lung cancer at our hospital between January 2014 and March 2021. First, the relationship between LAA% and respiratory function parameters (RFPs) calculated for both the bilateral and non-resected sides was used to estimate the most effective patient group. Next, multivariate analyses of the relationship between LAA% of the non-resected side and PRC were performed using logistic regression analysis after adjusting for basic patient attributes and respiratory function.
RESULTS: A correlation was found between LAA% and RFP in smoking males. Multivariate analysis showed a strong relationship between model 3, adjusted for basic patient attributes and lung function factors, and PRC (odds ratio, 2.43; 95% confidence interval, 1.05-5.63).
CONCLUSIONS: LAA% of the non-resected side suggested that it may be able to predict the occurrence of PRC after lung cancer lobectomy.
摘要：
目的：我们研究了术前评估未切除侧的低衰减面积百分比（LAA％）是否可以预测肺叶切除术后的术后呼吸道并发症（PRC）。
方法：我们在2014年1月至2021年3月期间在我院进行了217名吸烟者（男性175名，女性42名）原发性肺癌肺叶切除术的历史队列研究。首先,使用计算的双侧和非切除侧的LAA%与呼吸功能参数(RFP)之间的关系来估计最有效的患者组.接下来,在校正患者基本属性和呼吸功能后,使用logistic回归分析对未切除侧的LAA%与PRC之间的关系进行多变量分析.
结果：在吸烟男性中发现LAA％和RFP之间存在相关性。多变量分析显示模型3之间有很强的关系，校正了基本的患者属性和肺功能因素，和中国(赔率比，2.43；95%置信区间，1.05-5.63)。
结论：未切除侧的LAA％提示可能能够预测肺癌肺叶切除术后PRC的发生。
方法：我们在2014年1月至2021年3月期间在我院进行了217名吸烟者（男性175名，女性42名）原发性肺癌肺叶切除术的历史队列研究。首先,使用计算的双侧和非切除侧的LAA%与呼吸功能参数(RFP)之间的关系来估计最有效的患者组.接下来,在校正患者基本属性和呼吸功能后,使用logistic回归分析对未切除侧的LAA%与PRC之间的关系进行多变量分析.
结果：在吸烟男性中发现LAA％和RFP之间存在相关性。多变量分析显示模型3之间有很强的关系，校正了基本的患者属性和肺功能因素，和中国(赔率比，2.43；95%置信区间，1.05-5.63)。
结论：未切除侧的LAA％提示可能能够预测肺癌肺叶切除术后PRC的发生。
