METHODS: Hemoglobin A1c (HbA1c) levels were assessed 3 months (M3) and 6 months (M6) before the diagnosis of active CN (M0).
RESULTS: 103 patients living with diabetes and presenting active CN were included between January and December 2019 from the 31 centers participating in this study (30 in France and 1 in Belgium). The mean age of the participants was 60.2±12.2 years; the vast majority were men (71.8%) living with type 2 diabetes (75.5%). Mean HbA1c levels significantly declined between M6 (median 7.70; Q1, Q3: 7.00, 8.55) and M3 (median 7.65; Q1, Q3: 6.90, 8.50) (p=0.012), as well as between M6 and M0 (median 7.40; Q1, Q3: 6.50, 8.50) (p=0.014). No significant difference was found between M3 and M0 (p=0.072).
CONCLUSIONS: A significant reduction in HbA1c levels seems to accompany the onset of the active phase of CN.
BACKGROUND: NCM03744039.
方法:在诊断为活动性CN(M0)前3个月(M3)和6个月(M6)评估血红蛋白A1c(HbA1c)水平。
结果:在2019年1月至12月期间,来自参与本研究的31个中心(30个在法国,1个在比利时)的103名糖尿病患者被纳入。参与者的平均年龄为60.2±12.2岁;绝大多数是患有2型糖尿病(75.5%)的男性(71.8%)。平均HbA1c水平在M6(中位数7.70;Q1,Q3:7.00,8.55)和M3(中位数7.65;Q1,Q3:6.90,8.50)之间显着下降(p=0.012),以及M6和M0之间(中位数7.40;Q1,Q3:6.50,8.50)(p=0.014)。M3和M0之间没有发现显着差异(p=0.072)。
结论:HbA1c水平的显著降低似乎伴随着CN活跃期的开始。
背景:NCM03744039.