Abstract：
BACKGROUND: Pharmaceutical permanence (PP), outside the working hours of an in-house pharmacy (PUI), allows to guarantee the continuity of care in health-care institutions. A retrospective review of urgent drug dispensing was carried out in the light of changes in the drug circuit.
METHODS: The analysis of drug dispensations was performed over a period from 2011 to 2019. The average number of drugs dispensed per shift, annual dispensations, and their variation by day of the week were studied. The increase is statistically significant and is found on both weekdays and weekends. Each drug was identified according to its Anatomical Therapeutic Chemical (ATC) classification. Data on the activities of our institution (number of hospitalizations, average length of stay) were also collected.
RESULTS: In 2011, an average of 36 medications were dispensed per on-call period, compared with 77 in 2019 (a doubling of activity). The increase is statistically significant and is found on both weekdays and weekends. Neurological drugs and anti-infectives represent on average 43 % of the drugs dispensed. At the same time, there was a decrease in average length of stay and an increase in hospitalizations (-10 % and +16 % respectively).
CONCLUSIONS: The increase in the average number of medications dispensed per shift is notable. It reflects a strong and gradual increase in activity, which was increased when the full vacuum cabinets (FVCs) were introduced, which improved the quality and safety of the pharmaceutical circuit. The revision of the allocations and the information of prescribers on the drug circuit will optimize the activity and refocus it on the pharmaceutical analysis of urgent needs.
METHODS: The analysis of drug dispensations was performed over a period from 2011 to 2019. The average number of drugs dispensed per shift, annual dispensations, and their variation by day of the week were studied. The increase is statistically significant and is found on both weekdays and weekends. Each drug was identified according to its Anatomical Therapeutic Chemical (ATC) classification. Data on the activities of our institution (number of hospitalizations, average length of stay) were also collected.
RESULTS: In 2011, an average of 36 medications were dispensed per on-call period, compared with 77 in 2019 (a doubling of activity). The increase is statistically significant and is found on both weekdays and weekends. Neurological drugs and anti-infectives represent on average 43 % of the drugs dispensed. At the same time, there was a decrease in average length of stay and an increase in hospitalizations (-10 % and +16 % respectively).
CONCLUSIONS: The increase in the average number of medications dispensed per shift is notable. It reflects a strong and gradual increase in activity, which was increased when the full vacuum cabinets (FVCs) were introduced, which improved the quality and safety of the pharmaceutical circuit. The revision of the allocations and the information of prescribers on the drug circuit will optimize the activity and refocus it on the pharmaceutical analysis of urgent needs.
摘要：
背景：药物持久性（PP），在内部药房(PUI)的工作时间之外，允许保证医疗保健机构护理的连续性。根据药物回路的变化，对紧急药物分配进行了回顾性审查。
方法：在2011年至2019年的一段时间内对药物分配进行了分析。每班分配的平均药物数量，年度拨款，并研究了它们在一周中的变化。增加具有统计学意义，并且在工作日和周末都可以发现。根据其解剖治疗化学(ATC)分类鉴定每种药物。关于我们机构活动的数据(住院次数，平均停留时间)也被收集。
结果：2011年，平均每个待命期分配36种药物，与2019年的77相比（活动翻了一番）。增加具有统计学意义，并且在工作日和周末都可以发现。神经药物和抗感染药物平均占所分配药物的43%。同时,平均住院时间减少,住院次数增加(分别为-10%和+16%).
结论：每班分配的药物平均数量显著增加。它反映了活动的强烈和逐渐增加，当引入全真空柜(FVC)时，提高了制药回路的质量和安全性。对药物回路分配和处方者信息的修订将优化活动，并将其重新集中在紧急需求的药物分析上。
方法：在2011年至2019年的一段时间内对药物分配进行了分析。每班分配的平均药物数量，年度拨款，并研究了它们在一周中的变化。增加具有统计学意义，并且在工作日和周末都可以发现。根据其解剖治疗化学(ATC)分类鉴定每种药物。关于我们机构活动的数据(住院次数，平均停留时间)也被收集。
结果：2011年，平均每个待命期分配36种药物，与2019年的77相比（活动翻了一番）。增加具有统计学意义，并且在工作日和周末都可以发现。神经药物和抗感染药物平均占所分配药物的43%。同时,平均住院时间减少,住院次数增加(分别为-10%和+16%).
结论：每班分配的药物平均数量显著增加。它反映了活动的强烈和逐渐增加，当引入全真空柜(FVC)时，提高了制药回路的质量和安全性。对药物回路分配和处方者信息的修订将优化活动，并将其重新集中在紧急需求的药物分析上。
