PDF(Pubmed)
Abstract：
Giant cell tumor (GCT) of the bone is a benign, locally aggressive neoplasm of epiphyseal origin. Most common sites for GCTs include the distal femur, proximal tibia, and the distal end of radius with the distal humerus being involved rarely. GCT is predominantly managed by extended curettage followed by adjuvant therapy to reduce recurrence. Juxta-articular GCTs are difficult to manage due to the destruction of the articular cartilage and subchondral bone which necessitates the need for joint reconstruction or fusion to salvage the joint. Aggressive and recurrent GCTs can be managed by wide resection of the tumor to reduce local recurrence followed by joint reconstruction or fusion. Joint reconstruction using a total elbow arthroplasty has been described for limb salvage as it provides a good functional outcome. We present a case of an aggressive GCT of the distal humerus that was treated using wide resection with humero-ulnar arthrodesis as an alternative in situations where joint reconstruction is not possible due to the unavailability of the prosthesis or socio-economic factors. The patient was asymptomatic after two years of follow-up, had no signs of recurrence, and had good hand functions.
摘要：
骨巨细胞瘤(GCT)是一种良性,骨phy起源的局部侵袭性肿瘤。GCT最常见的部位包括股骨远端，胫骨近端,桡骨远端很少累及肱骨远端。GCT主要通过延长刮宫术，然后进行辅助治疗以减少复发。由于关节软骨和软骨下骨的破坏,近关节GCT难以管理,这需要关节重建或融合以挽救关节。侵袭性和复发性GCT可以通过广泛切除肿瘤以减少局部复发，然后进行关节重建或融合来管理。已经描述了使用全肘关节成形术进行关节重建以挽救肢体，因为它提供了良好的功能效果。我们介绍了一例肱骨远端侵袭性GCT的病例，该病例在由于假体不可用或社会经济因素而无法进行关节重建的情况下，采用广泛切除的肱骨尺骨关节固定术作为替代方法。经过两年的随访，患者无症状，没有复发的迹象,并具有良好的手部功能。
