关键词: flap imaging radiotherapy reconstructive surgery sinonasal tumors

来  源:   DOI:10.3389/fonc.2022.1013801   PDF(Pubmed)

Abstract:
In sinonasal cancer surgery, a fundamental challenge is to understand the postoperative imaging changes after reconstruction. Misinterpretation of post-operative imaging may lead to a misdiagnosis of tumor recurrence. Because radiotherapy planning is based on imaging, there are many gaps in knowledge to be filled in the interpretation of postoperative imaging to properly define radiotherapy tumor volumes in the presence of flaps. On the other hand, radiotherapy may be responsible for tissue fibrosis or atrophy, the anatomy of the reconstructed region and the functional outcomes may change after radiotherapy compared to surgery alone. This narrative review illustrates the interdisciplinary aims and challenges of sinonasal reconstructive surgery using flaps or grafts. It is particularly relevant to radiologists and radiation oncologists, at a time when intensity modulated radiotherapy and proton therapy have the potential to further contribute to reduction of morbidity.
摘要:
在鼻窦癌手术中,一个基本的挑战是了解重建后的术后影像学变化。术后影像学的误解可能导致肿瘤复发的误诊。因为放射治疗计划是基于成像的,在术后影像学的解释中,有许多知识空白需要填补,以正确定义存在皮瓣的放射治疗肿瘤体积。另一方面,放疗可能导致组织纤维化或萎缩,与单纯手术相比,放疗后重建区域的解剖结构和功能结局可能会发生变化。这篇叙述性综述说明了使用皮瓣或移植物进行鼻窦重建手术的跨学科目标和挑战。它与放射科医生和放射肿瘤学家特别相关,在调强放疗和质子治疗有可能进一步有助于降低发病率的时候。

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