关键词: Fibrotic hypersensitivity pneumonitis high-resolution CT histopathology interstitial lung disease non-fibrotic hypersensitivity pneumonitis

来  源:   DOI:10.1016/j.rcl.2022.06.013

Abstract:
Hypersensitivity pneumonia (HP) refers to a heterogeneous group of interstitial lung diseases resulting from a non-IgE immune-mediated reaction to inhaled pathogens in susceptible and sensitized hosts. Environmental and genetic factors are important substrates of disease pathogenesis. A recurrent or ongoing airborne exposure results in activation of humoral and cellular immune responses. This article discusses key clinical, radiologic, and histopathologic features of HP and reviews current recommendations.
摘要:
超敏反应性肺炎(HP)是指由易感和致敏宿主中对吸入病原体的非IgE免疫介导的反应引起的一组间质性肺病。环境和遗传因素是疾病发病的重要基础。反复或持续的空气传播暴露导致体液和细胞免疫应答的激活。本文讨论了关键的临床,放射学,和HP的组织病理学特征,并回顾目前的建议。
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