PDF(Pubmed)
Abstract：
Langerhans cell histiocytosis (LCH) and adult-onset xanthogranuloma (AXG) are rare disorders characterized by the accumulation of macrophage, dendritic cells, or monocyte-derived cells in various tissues of the body. Many researchers now consider LCH a form of malignancy, but this classification remains controversial. As per our knowledge, there are only 36 cases of AXG reported so far in the English literature. Here, we report a case of AXG and single-system LCH found in the oral cavity and cervical lymph nodes, respectively. In this article, we intend to define a clear understanding of some classic clinical, radiological, and histopathological findings of LCH and AXG, to differentiate them from oral malignancies. The primary goal of this article is to increase awareness regarding conditions that closely resemble malignancies and to save patients from the burden of extensive treatment under the presumption of malignant disorders. In the medical field, reporting of rare cases is highly encouraged; however, proper treatment for the patient depends on the accurate diagnosis that, in this case, was made postoperatively, which only added more physical and mental distress for the patient and their family.
摘要：
朗格汉斯细胞组织细胞增生症（LCH）和成年发作的黄色肉芽肿（AXG）是罕见的疾病，其特征是巨噬细胞的积累，树突状细胞,或身体各种组织中的单核细胞来源的细胞。许多研究人员现在认为LCH是一种恶性肿瘤，但是这种分类仍然存在争议。根据我们的知识,到目前为止，英语文献中只有36例AXG报告。这里,我们报告了一例在口腔和颈部淋巴结中发现的AXG和单系统LCH，分别。在这篇文章中,我们打算对一些经典的临床有一个清晰的理解，放射学,以及LCH和AXG的组织病理学发现，将它们与口腔恶性肿瘤区分开来。本文的主要目标是提高人们对与恶性肿瘤极为相似的疾病的认识，并在恶性疾病的推定下使患者摆脱广泛治疗的负担。在医学领域,非常鼓励报告罕见病例；然而，正确的治疗取决于准确的诊断，在这种情况下,是术后做的，这只会给患者及其家人带来更多的身心困扰。
