关键词: infant low- and lower-middle-income countries neonatal mortality premature neonate prematurity short-term outcomes survival very low birth weight (VLBW) infant low- and lower-middle-income countries neonatal mortality premature neonate prematurity short-term outcomes survival very low birth weight (VLBW)

来  源:   DOI:10.3389/fped.2022.930338   PDF(Pubmed)

Abstract:
UNASSIGNED: The neonatal mortality rate in South Africa is lower than the global average, but still approximately five times higher than some European and Scandinavian countries. Prematurity, and its complications, is the main cause (35%) of neonatal deaths.
UNASSIGNED: To review the maternal, delivery period and infant characteristics in relation to mortality in very low birth weight (VLBW) infants at Charlotte Maxeke Johannesburg Academic Hospital (CMJAH).
UNASSIGNED: This was a retrospective descriptive study of VLBW infants admitted to CMJAH between 1 January 2017 and 31 December 2018. All infants with a birth weight between 500 to ≤ 1,500 grams were included. The characteristics and survival of these infants were described using univariate analysis.
UNASSIGNED: Overall survival was 66.5%. Provision of antenatal steroids, antenatal care, Cesarean section, female sex, resuscitation at birth, and 5-min Apgar score more than five was related with better survival to discharge. Among respiratory diagnoses, 82.8% were diagnosed with RDS, 70.8% received surfactant therapy and 90.7% received non-invasive respiratory support after resuscitation. At discharge, 59.5% of the mothers were breastfeeding and 30.8% spent time in kangaroo mother care.
UNASSIGNED: The two-thirds survival rate of VLBW infants is similar to those in other developing countries but still remains lower than developed countries. This may be improved with better antenatal care attendance, coverage of antenatal steroids, temperature control after birth, improving infection prevention and control practices, breastfeeding rates and kangaroo mother care. The survival rate was lowest amongst extremely low birth weight (ELBW) infants.
摘要:
UNASSIGNED:南非的新生儿死亡率低于全球平均水平,但仍比一些欧洲和斯堪的纳维亚国家高出约五倍。早产,和它的并发症,是新生儿死亡的主要原因(35%)。
未经批准:要检查产妇,CharlotteMaxeke约翰内斯堡学术医院(CMJAH)的极低出生体重(VLBW)婴儿的分娩期和婴儿特征与死亡率的关系。
UNASSIGNED:这是一项对2017年1月1日至2018年12月31日期间接受CMJAH的VLBW婴儿的回顾性描述性研究。包括所有出生体重在500至≤1,500克之间的婴儿。使用单变量分析描述了这些婴儿的特征和存活。
未经授权:总生存率为66.5%。提供产前类固醇,产前保健,剖腹产,女性性别,出生时复苏,5分钟Apgar评分超过5分与更好的出院生存率相关。在呼吸道诊断中,82.8%被诊断为RDS,70.8%接受表面活性剂治疗,90.7%在复苏后接受无创呼吸支持。出院时,59.5%的母亲母乳喂养,30.8%的母亲在袋鼠母亲护理中度过了时间。
UNASSIGNED:VLBW婴儿的三分之二存活率与其他发展中国家相似,但仍低于发达国家。这可以通过更好的产前护理得到改善,产前类固醇的覆盖率,出生后的温度控制,改善感染预防和控制措施,母乳喂养率和袋鼠母亲护理。极低出生体重(ELBW)婴儿的存活率最低。
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