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Abstract：
Introduction Prompt recognition and aggressive management of acute intoxication due to organophosphorus poisoning are essential to minimize the morbidity and mortality. The present study was undertaken to know the prognosis and outcome of organophosphorus poisoning patients with the estimation of low-cost enzymes like the serum amylase level in a population with financial constraints. Methods In this cross-sectional study, we had enrolled 100 cases that had a history of exposure to organophosphorus compounds, and the serum amylase level was measured in all the patients. We assessed the outcome of all the patients in the form of discharge, need of ventilators, intensive care unit stay, and death. Results The mean serum amylase level in discharge patients was 335.40 ± 192.45, and in the patients who died it was 843.37 ± 22.60. It was significant to predict the outcome ( t -value 7.07, p -value 0.0001, statistically significant). Conclusion Serum amylase level shows significant correlation with clinical outcomes in organophosphorus poisoning.
摘要：
简介迅速识别和积极管理急性中毒由于有机磷中毒是必不可少的，以减少发病率和死亡率。进行本研究是为了了解有机磷中毒患者的预后和结果，并评估了经济困难人群中的低成本酶，例如血清淀粉酶水平。方法在这项横断面研究中，我们招募了100例有有机磷化合物接触史的病例，并测定所有患者的血清淀粉酶水平。我们以出院的形式评估了所有患者的预后，需要呼吸机，重症监护室逗留,和死亡。结果出院患者的平均血清淀粉酶水平为335.40±192.45，死亡患者的平均血清淀粉酶水平为843.37±22.60。预测结果具有重要意义（t值7.07，p值0.0001，统计学意义）。结论血清淀粉酶水平与有机磷中毒的临床结局有显著的相关性。
