Abstract:
There is limited data on the impact of atrial fibrillation (Afib) on hospital outcomes in females with peripartum cardiomyopathy (PPCM). The National Inpatient Sample (NIS) 2011-2019 was used to find patients with PPCM. PPCM patients were divided into two groups: with and without Afib. Baseline characteristics were compared between both groups. Logistic regression was used to find independent predictors of Afib. Out of 13,840 PPCM patients, 249 (1.8%) also had a diagnosis of Afib. The Afib group was older and had a high burden of comorbidities. PPCM patients with Afib had higher in-hospital mortality (4-vs-0.7%, p=0.02), mean length of stay (11.3-vs-4.3 days, p<0.001) and healthcare resource utilization. Old age, low-income quartile, liver disease, obstructive sleep apnea and acute posthemorrhagic anemia were significant predictors of Afib. In conclusion, Afib is associated with higher in-hospital mortality and worse outcomes in females with PPCM. Further research is needed to improve these outcomes.
摘要:
关于房颤(Afib)对围产期心肌病(PPCM)女性的医院结局的影响的数据有限。2011-2019年全国住院患者样本(NIS)用于寻找PPCM患者。PPCM患者分为两组:有和没有Afib。比较两组的基线特征。Logistic回归用于寻找Afib的独立预测因子。在13840名PPCM患者中,249(1.8%)也诊断为Afib。Afib组年龄较大,合并症负担很高。患有Afib的PPCM患者的院内死亡率更高(4-vs-0.7%,p=0.02),平均住院时间(11.3-vs-4.3天,p<0.001)和医疗资源利用率。老年,低收入四分位数,肝病,阻塞性睡眠呼吸暂停和急性出血后贫血是Afib的重要预测因子。总之,Afib与PPCM女性患者住院死亡率较高和预后较差相关。需要进一步的研究来改善这些结果。