COVID-19-Induced Myocarditis and mRNA Vaccine-Related Pericarditis: A Case Report.

COVID - 19 诱导的心肌炎和 mRNA 疫苗相关心包炎 ： 病例报告。

• 发表时间: Aug 2022
• 来源期刊: Cureus
• DOI: 10.7759/cureus.28440
• PMID: 36176830
• 文章类型: Case Reports
• 作者列表: Voltarelli CL,Silva L,Longo M,Ferraria S,Martins LL,Nazar G,Magalhães T,Miyazima R,Lenci Marques G,Voltarelli CL,Silva L,Longo M,Ferraria S,Martins LL,Nazar G,Magalhães T,Miyazima R,Lenci Marques G

关键词: bnt162b2 mrna vaccine; covid 19; covid and myocarditis; heart failure; pericardial diseases; perimyocarditis; bnt162b2 mrna vaccine; covid 19; covid and myocarditis; heart failure; pericardial diseases; perimyocarditis

Abstract

Acute inflammatory cardiac disease is an increasing cause of COVID-19 vaccine-induced complications. We report a case of acute pericarditis following the second dose of the COVID-19 vaccine (BNT162b2) in a 49-year-old woman with previous COVID-19-induced myocarditis and heart failure. A clinical presentation compatible with acute decompensated heart failure elevated troponin levels and a cardiac-MRI showing myocardial fibrosis and inflammatory pericardial effusion led to the diagnosis of perimyocarditis. She was treated with non-steroidal anti-inflammatory drugs (NSAIDs) and colchicine. Her condition improved in eight days. Physicians should be aware of the possible diagnosis of pericarditis and/or a myocardial injury after COVID-19 infection and vaccination.

摘要

急性炎症性心脏病是COVID-19疫苗引起的并发症的增加原因。我们报告了一名49岁女性在第二剂COVID-19疫苗（BNT162b2）后出现急性心包炎的病例，该女性先前患有COVID-19诱发的心肌炎和心力衰竭。与急性失代偿性心力衰竭相符的临床表现是肌钙蛋白水平升高，心脏MRI显示心肌纤维化和炎性心包积液可诊断为心包炎。她接受了非甾体抗炎药（NSAIDs）和秋水仙碱治疗。她的病情在八天内得到了改善。医生应了解COVID-19感染和疫苗接种后可能诊断为心包炎和/或心肌损伤。