PDF(Pubmed)
Abstract：
Thromboangitis obliterans or Buerger\'s disease is a segmental inflammatory condition of small and medium-sized arteries and veins. It is commonly seen in males with age under 45 years and with a current or recent history of tobacco use, and in smokers. It is sporadic in young women. This report describes a primigravida with dry gangrene in both upper and lower limbs because of Buerger\'s disease. The primary diagnosis of the disease occurred first time in pregnancy at the 17th week of gestation with the patient reporting dry gangrene and pain in the digits and confirmed with a non-invasive Doppler study. The patient was screened for autoimmune diseases, diabetes mellitus, and the presence of hypercoagulable disorders. Echocardiography and arteriography were performed to rule out any source of emboli. The case report aims to discuss a rare diagnostic and therapeutic dilemma in the case of a pregnant woman presenting with gangrene without any history of tobacco addiction.
摘要：
血栓闭塞性脉管炎或Buerger病是中小型动脉和静脉的节段性炎症。常见于年龄在45岁以下且有当前或近期烟草使用史的男性，和吸烟者。它在年轻女性中零星出现。该报告描述了由于Buerger病而导致上肢和下肢干性坏疽的primigravida。该疾病的初步诊断首次发生在妊娠第17周，患者报告干性坏疽和手指疼痛，并通过非侵入性多普勒研究证实。患者接受了自身免疫性疾病筛查，糖尿病,和高凝紊乱的存在。进行超声心动图和动脉造影以排除任何栓子来源。病例报告旨在讨论在孕妇出现坏疽而没有任何烟草成瘾史的情况下罕见的诊断和治疗困境。
