PDF(Pubmed)
Abstract：
BACKGROUND: A recent systematic review published in Head and Neck Pathology found that 3.8% of dentinogenic ghost cell tumors harbor duct-like/ cribriform architecture. Herein we discuss this finding regarding the differential diagnosis of this tumor with adenoid ameloblastoma.
METHODS: A critical review of some microscopic findings reported in a recent paper published in the Head and Neck Pathology Journal was done.
RESULTS: Although there are overlapping microscopic features with dentinogenic ghost cell tumor, adenoid ameloblastoma is distinguished by the combination of duct-like structures and whorls/morules. In our opinion, at least some cases previously diagnosed as dentinogenic ghost cell tumors may now be more accurately classified as adenoid ameloblastoma.
CONCLUSIONS: We conclude that a reassessment of dentinogenic ghost cell tumor cases using the diagnostic criteria proposed by the new WHO classification of Head and Neck Tumors (2022) is warranted.
METHODS: A critical review of some microscopic findings reported in a recent paper published in the Head and Neck Pathology Journal was done.
RESULTS: Although there are overlapping microscopic features with dentinogenic ghost cell tumor, adenoid ameloblastoma is distinguished by the combination of duct-like structures and whorls/morules. In our opinion, at least some cases previously diagnosed as dentinogenic ghost cell tumors may now be more accurately classified as adenoid ameloblastoma.
CONCLUSIONS: We conclude that a reassessment of dentinogenic ghost cell tumor cases using the diagnostic criteria proposed by the new WHO classification of Head and Neck Tumors (2022) is warranted.
摘要：
背景：最近发表在《头颈部病理学》上的一项系统评价发现，3.8%的牙源性鬼细胞瘤具有导管样/筛状结构。在此，我们讨论有关该肿瘤与腺样成釉细胞瘤的鉴别诊断的这一发现。
方法：对最近发表在《头颈部病理学杂志》上的一篇论文中报道的一些微观发现进行了严格审查。
结果：尽管牙本质鬼细胞瘤有重叠的微观特征，腺样体成釉细胞瘤的特征在于导管样结构和螺纹/磨牙的组合。在我们看来,至少一些以前诊断为牙源性鬼细胞瘤的病例现在可以更准确地分类为腺样成釉细胞瘤。
结论：我们得出结论，使用新的WHO头颈部肿瘤分类（2022）提出的诊断标准重新评估牙源性鬼细胞瘤病例是必要的。
方法：对最近发表在《头颈部病理学杂志》上的一篇论文中报道的一些微观发现进行了严格审查。
结果：尽管牙本质鬼细胞瘤有重叠的微观特征，腺样体成釉细胞瘤的特征在于导管样结构和螺纹/磨牙的组合。在我们看来,至少一些以前诊断为牙源性鬼细胞瘤的病例现在可以更准确地分类为腺样成釉细胞瘤。
结论：我们得出结论，使用新的WHO头颈部肿瘤分类（2022）提出的诊断标准重新评估牙源性鬼细胞瘤病例是必要的。
