Abstract：
OBJECTIVE: The purpose of this study was to examine socio-demographic, lifestyle and ophthalmological factors associated with poorer Vision Related Quality of Life (VRQoL) in people with glaucoma.
METHODS: This cross-sectional study included 306 consecutive patients with glaucoma who presented for regular check-ups at the referral center in Belgrade (Serbia) from August 2015 to September 2016. The diagnosis of glaucoma was based on the glaucomatous disc cupping and reproducible visual field impairment on one or both eyes. Quality of life was examined using the validated Glaucoma Quality of Life-15 (GQL-15) and the National Eye Institute Visual Function Questionnaire 25 (NEI VFQ 25).
RESULTS: A series of adjusted linear regression models showed that glaucoma patients with higher educational attainment, who were employed and still driving had better VRQoL. Worse visual acuity and visual field defect, being in later glaucoma stages, having lower intraocular pressure, having two laser interventions as well as having pseudo-exfoliative glaucoma was associated with worse VRQoL. Intake of fewer medications and having had no trabeculectomies on better eye as well as taking less drops per day on worse eye were associated with better VRQoL.
CONCLUSIONS: Several socio-demographic, lifestyle and ocular factors can impact VRQoL in glaucoma patients. Identifying people who are at risk of having worse VRQoL could allow for earlier interventions, such as changes in therapy, undergoing surgery, use of mobility aids etc.
METHODS: This cross-sectional study included 306 consecutive patients with glaucoma who presented for regular check-ups at the referral center in Belgrade (Serbia) from August 2015 to September 2016. The diagnosis of glaucoma was based on the glaucomatous disc cupping and reproducible visual field impairment on one or both eyes. Quality of life was examined using the validated Glaucoma Quality of Life-15 (GQL-15) and the National Eye Institute Visual Function Questionnaire 25 (NEI VFQ 25).
RESULTS: A series of adjusted linear regression models showed that glaucoma patients with higher educational attainment, who were employed and still driving had better VRQoL. Worse visual acuity and visual field defect, being in later glaucoma stages, having lower intraocular pressure, having two laser interventions as well as having pseudo-exfoliative glaucoma was associated with worse VRQoL. Intake of fewer medications and having had no trabeculectomies on better eye as well as taking less drops per day on worse eye were associated with better VRQoL.
CONCLUSIONS: Several socio-demographic, lifestyle and ocular factors can impact VRQoL in glaucoma patients. Identifying people who are at risk of having worse VRQoL could allow for earlier interventions, such as changes in therapy, undergoing surgery, use of mobility aids etc.
摘要：
目的：这项研究的目的是检查社会人口统计学，生活方式和眼科因素与青光眼患者视力相关生活质量(VRQoL)较差相关
方法：本横断面研究纳入了2015年8月至2016年9月在贝尔格莱德（塞尔维亚）的转诊中心接受定期检查的306例连续青光眼患者。青光眼的诊断基于青光眼视盘拔罐和一只或两只眼睛的可重复视野损害。使用经过验证的青光眼生活质量-15(GQL-15)和国家眼科研究所视觉功能问卷25(NEIVFQ25)检查生活质量。
结果：一系列调整后的线性回归模型显示，受教育程度较高的青光眼患者，受雇且仍在开车的人有更好的VRQoL。更糟糕的视力和视野缺陷，处于晚期青光眼阶段，具有较低的眼压，进行两次激光干预以及假性剥脱性青光眼与较差的VRQoL相关。服用更少的药物和在较好的眼睛上没有小梁切除术以及在较差的眼睛上每天服用更少的滴剂与更好的VRQoL相关。
结论：几个社会人口统计学，生活方式和眼部因素可影响青光眼患者的VRQoL。确定有风险的VRQoL较差的人可以进行早期干预，比如治疗的改变，正在接受手术,使用助行器等.
方法：本横断面研究纳入了2015年8月至2016年9月在贝尔格莱德（塞尔维亚）的转诊中心接受定期检查的306例连续青光眼患者。青光眼的诊断基于青光眼视盘拔罐和一只或两只眼睛的可重复视野损害。使用经过验证的青光眼生活质量-15(GQL-15)和国家眼科研究所视觉功能问卷25(NEIVFQ25)检查生活质量。
结果：一系列调整后的线性回归模型显示，受教育程度较高的青光眼患者，受雇且仍在开车的人有更好的VRQoL。更糟糕的视力和视野缺陷，处于晚期青光眼阶段，具有较低的眼压，进行两次激光干预以及假性剥脱性青光眼与较差的VRQoL相关。服用更少的药物和在较好的眼睛上没有小梁切除术以及在较差的眼睛上每天服用更少的滴剂与更好的VRQoL相关。
结论：几个社会人口统计学，生活方式和眼部因素可影响青光眼患者的VRQoL。确定有风险的VRQoL较差的人可以进行早期干预，比如治疗的改变，正在接受手术,使用助行器等.
