PDF(Pubmed)
Abstract：
UNASSIGNED: Thalassemia major (TM) is a severe life-threatening hemoglobinopathy. It causes a typical chipmunk face due to increased hematopoiesis. Severe malocclusion often accompanies facial deformity, which may affect Oral Health-related Quality of Life (OHRQoL). The aim of this study was to assess the relationship between orthodontic treatment needs and OHRQoL in TM patients.
UNASSIGNED: One hundred and five adult patients with TM participated in this cross-sectional study. Oral Health Impact Profile-14 (OHIP-14) questionnaire was used to measure OHRQoL and the patient\'s need for orthodontic treatment was evaluated using the Index of Orthodontic Treatment Need (IOTN). The comparison of OHIP-14 scores between groups regarding orthodontic treatment need was carried out using t-test (SPSS software); P < 0.05 was considered statistically significant.
UNASSIGNED: The mean age of participants was 24.92 (±9.33) years, with 52% female versus 48% male. Orthodontic treatment need was 27.6%. The mean score of OHIP-14 was 12.95 (±7.02). A statistically significant relationship was found between OHIP-14 score and age, gender, and orthodontic treatment need (P < 0.05). All domains of OHIP-14 were significantly related to orthodontic treatment need (P < 0.05), except for \"physical disability\" (P = 0.282).
UNASSIGNED: OHRQoL was lower in TM patients with orthodontic treatment needs. Planning to treat malocclusion seems necessary to improve the quality of life in these patients.
UNASSIGNED: One hundred and five adult patients with TM participated in this cross-sectional study. Oral Health Impact Profile-14 (OHIP-14) questionnaire was used to measure OHRQoL and the patient\'s need for orthodontic treatment was evaluated using the Index of Orthodontic Treatment Need (IOTN). The comparison of OHIP-14 scores between groups regarding orthodontic treatment need was carried out using t-test (SPSS software); P < 0.05 was considered statistically significant.
UNASSIGNED: The mean age of participants was 24.92 (±9.33) years, with 52% female versus 48% male. Orthodontic treatment need was 27.6%. The mean score of OHIP-14 was 12.95 (±7.02). A statistically significant relationship was found between OHIP-14 score and age, gender, and orthodontic treatment need (P < 0.05). All domains of OHIP-14 were significantly related to orthodontic treatment need (P < 0.05), except for \"physical disability\" (P = 0.282).
UNASSIGNED: OHRQoL was lower in TM patients with orthodontic treatment needs. Planning to treat malocclusion seems necessary to improve the quality of life in these patients.
摘要：
未经证实：重型地中海贫血（TM）是一种严重的危及生命的血红蛋白病。由于造血功能增加，它会导致典型的花栗鼠脸。严重的错牙合畸形常伴随面部畸形，这可能会影响口腔健康相关的生活质量（OHRQoL）。这项研究的目的是评估TM患者正畸治疗需求与OHRQoL之间的关系。
UNASSIGNED：105名患有TM的成年患者参加了这项横断面研究。口腔健康影响概况-14（OHIP-14）问卷用于测量OHRQoL，并使用正畸治疗需求指数（IOTN）评估患者的正畸治疗需求。关于正畸治疗需要的OHIP-14评分组间比较采用t检验(SPSS软件);P<0.05被认为有统计学意义。
未经评估：参与者的平均年龄为24.92（±9.33）岁，女性为52%，男性为48%。正畸治疗需求为27.6%。OHIP-14的平均得分为12.95（±7.02）。发现OHIP-14评分与年龄之间存在统计学上的显着关系，性别,和正畸治疗的需要(P<0.05)。OHIP-14的所有域均与正畸治疗需求显着相关（P<0.05），除了“身体残疾”(P=0.282)。
UNASSIGNED：有正畸治疗需求的TM患者OHRQoL较低。计划治疗错牙合畸形似乎有必要改善这些患者的生活质量。
UNASSIGNED：105名患有TM的成年患者参加了这项横断面研究。口腔健康影响概况-14（OHIP-14）问卷用于测量OHRQoL，并使用正畸治疗需求指数（IOTN）评估患者的正畸治疗需求。关于正畸治疗需要的OHIP-14评分组间比较采用t检验(SPSS软件);P<0.05被认为有统计学意义。
未经评估：参与者的平均年龄为24.92（±9.33）岁，女性为52%，男性为48%。正畸治疗需求为27.6%。OHIP-14的平均得分为12.95（±7.02）。发现OHIP-14评分与年龄之间存在统计学上的显着关系，性别,和正畸治疗的需要(P<0.05)。OHIP-14的所有域均与正畸治疗需求显着相关（P<0.05），除了“身体残疾”(P=0.282)。
UNASSIGNED：有正畸治疗需求的TM患者OHRQoL较低。计划治疗错牙合畸形似乎有必要改善这些患者的生活质量。
