关键词: ACLF, Acute on chronic liver failure AIH, Autoimmune Hepatitis AKI, Acute kidney injury ALT, Alanine transaminase ANA, Antinuclear antibody ART, Antiretroviral therapy ASMA, Anti smooth muscle antibody AST, Aspartate aminotransferase CAM, Complementary and alternative medications DILI, Drug-induced liver injury GGT, Gamma-transferase HAV, Hepatitis A Virus HEV, Hepatitis E Virus HIV, Human immunodeficiency Virus IRIS, Immune reconstitution inflammatory syndrome LFT, Liver function test PHG, portal hypertensive gastropathy TJLB, Transjugular liver biopsy autoimmune hepatitis (AIH) cART, Combination antiretroviral therapy drug-induced liver injury – AIH (DILI-AIH) human immunodeficiency virus (HIV) iAIH, Denovo Idiopathic AIH

来  源:   DOI:10.1016/j.jceh.2022.05.003   PDF(Pubmed)

Abstract:
Autoimmune Hepatitis (AIH) is a chronic liver disease Characterized by interface hepatitis, lymphoplasmacytic infiltrate, and hepatic rosettes. HIV infection is a state of immunosuppression; hence, the possibility of AIH is relatively rare, especially in patients with low CD4 counts. Therefore, we present an interesting case series of four patients with autoimmune liver disease with myriad presentations for the first time from India. We propose that despite the rarity of this presentation with immunosuppression, one should never miss such a treatable cause of liver disease leading to good clinical outcomes.
摘要:
自身免疫性肝炎(AIH)是一种以界面性肝炎为特征的慢性肝病,淋巴浆细胞浸润,和肝玫瑰花结。HIV感染是一种免疫抑制状态;因此,AIH的可能性相对较少,尤其是CD4计数低的患者。因此,我们提出了一个有趣的病例系列,其中包括4例自身免疫性肝病患者,首次来自印度。我们建议,尽管这种表现很少与免疫抑制有关,一个人不应该错过这样一个可治疗的肝脏疾病的原因,导致良好的临床结果。
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