PDF(Pubmed)
Abstract：
BACKGROUND: The present study aimed to investigate differences in survivorship between medial and lateral unicompartmental knee arthroplasty (UKA) by analyzing the data of an Italian regional registry. The hypothesis was that, according to recent literature, lateral implants have comparable survivorship with regard to the medial implants.
METHODS: The Register of Orthopaedic Prosthetic Implants (RIPO) of Emilia-Romagna (Italy) database was searched for all UKAs between July 1, 2000, and December 31, 2019. For both cohorts, subject demographics and reasons for revision were presented as a percentage of the total cohort. Kaplan-Meier survivorship analysis was performed using revision of any component as the endpoint and survival times of unrevised UKAs taken as the last observation date (December 31, 2019, or date of death).
RESULTS: Patients living outside the region and symmetrical implants (which do not allow the compartment operated to be traced) were excluded. 5571 UKAs implanted on 5172 patients (5215 medial UKAs and 356 lateral UKAs) were included in the study. The survivorship analysis revealed 13 failures out of 356 lateral UKAs (3.7%) at a mean follow-up of 6.3 years and 495 failures out of 5215 medial UKAs (9.5%) at a mean follow-up of 6.7 years. The medial UKAs had a significantly higher risk of failure, with a Hazard Ratio of 2.6 (CI 95% 1.6-4.8; p < 0.001), adjusted for age, gender, weight, and mobility of the insert. Both the groups revealed a good survival rate, with 95.2% of lateral implants and 87.5% of medial implants still in situ at 10 years of follow-up.
CONCLUSIONS: Lateral UKA is a safe procedure showing longer survivorship than medial UKAs (95.2% and 87.5% at 10 years, respectively) in the present study.
METHODS: Level 3, therapeutic study.
METHODS: The Register of Orthopaedic Prosthetic Implants (RIPO) of Emilia-Romagna (Italy) database was searched for all UKAs between July 1, 2000, and December 31, 2019. For both cohorts, subject demographics and reasons for revision were presented as a percentage of the total cohort. Kaplan-Meier survivorship analysis was performed using revision of any component as the endpoint and survival times of unrevised UKAs taken as the last observation date (December 31, 2019, or date of death).
RESULTS: Patients living outside the region and symmetrical implants (which do not allow the compartment operated to be traced) were excluded. 5571 UKAs implanted on 5172 patients (5215 medial UKAs and 356 lateral UKAs) were included in the study. The survivorship analysis revealed 13 failures out of 356 lateral UKAs (3.7%) at a mean follow-up of 6.3 years and 495 failures out of 5215 medial UKAs (9.5%) at a mean follow-up of 6.7 years. The medial UKAs had a significantly higher risk of failure, with a Hazard Ratio of 2.6 (CI 95% 1.6-4.8; p < 0.001), adjusted for age, gender, weight, and mobility of the insert. Both the groups revealed a good survival rate, with 95.2% of lateral implants and 87.5% of medial implants still in situ at 10 years of follow-up.
CONCLUSIONS: Lateral UKA is a safe procedure showing longer survivorship than medial UKAs (95.2% and 87.5% at 10 years, respectively) in the present study.
METHODS: Level 3, therapeutic study.
摘要：
背景：本研究旨在通过分析意大利地区注册的数据来研究内侧和外侧单室膝关节置换术（UKA）之间的生存率差异。假设是，根据最近的文献，外侧植入物与内侧植入物具有相当的存活率。
方法：在2000年7月1日至2019年12月31日之间，对Emilia-Romagna（意大利）数据库的骨科假体植入物（RIPO）进行了搜索。对于这两个队列，受试者的人口统计学特征和修订原因以占总队列的百分比表示.Kaplan-Meier生存分析使用任何组件的修订作为终点，未修订的UKA的生存时间作为最后观察日期（2019年12月31日或死亡日期）。
结果：排除了住在该区域外和对称植入物（不允许追踪手术室）的患者。该研究包括在5172名患者中植入的5571个UKAs（5215个内侧UKAs和356个外侧UKAs）。生存分析显示，平均随访6.3年，在356个外侧UKA（3.7％）中有13个失败，在平均随访6.7年的5215个内侧UKA（9.5％）中有495个失败。中间UKA的失败风险明显更高，危险比为2.6（CI95%1.6-4.8；p<0.001），根据年龄调整，性别,体重,插入件的移动性。两组都显示出良好的生存率，在10年的随访中，95.2％的外侧植入物和87.5％的内侧植入物仍在原位。
结论：外侧UKA是一种安全的手术，其存活率比内侧UKA更长（10年时分别为95.2％和87.5％，分别)在本研究中。
方法：3级，治疗性研究。
方法：在2000年7月1日至2019年12月31日之间，对Emilia-Romagna（意大利）数据库的骨科假体植入物（RIPO）进行了搜索。对于这两个队列，受试者的人口统计学特征和修订原因以占总队列的百分比表示.Kaplan-Meier生存分析使用任何组件的修订作为终点，未修订的UKA的生存时间作为最后观察日期（2019年12月31日或死亡日期）。
结果：排除了住在该区域外和对称植入物（不允许追踪手术室）的患者。该研究包括在5172名患者中植入的5571个UKAs（5215个内侧UKAs和356个外侧UKAs）。生存分析显示，平均随访6.3年，在356个外侧UKA（3.7％）中有13个失败，在平均随访6.7年的5215个内侧UKA（9.5％）中有495个失败。中间UKA的失败风险明显更高，危险比为2.6（CI95%1.6-4.8；p<0.001），根据年龄调整，性别,体重,插入件的移动性。两组都显示出良好的生存率，在10年的随访中，95.2％的外侧植入物和87.5％的内侧植入物仍在原位。
结论：外侧UKA是一种安全的手术，其存活率比内侧UKA更长（10年时分别为95.2％和87.5％，分别)在本研究中。
方法：3级，治疗性研究。
