PDF(Pubmed)
Abstract：
UNASSIGNED: Millions of patients admitted globally in health care setups require insertion of peripheral intravascular catheter for intravenous drugs or fluid administration. However, if proper precautions are not followed during insertion, it results in significant morbidity. This study was designed to study the efficacy and safety of recommended Centre for Disease Control and Prevention (CDC) guidelines for peripheral intravascular catheter insertion practice and its comparison with a standard insertion protocol being followed and their outcome.
UNASSIGNED: Patients were randomized and catheter was inserted as recommended by CDC guideline (Group 1, n = 100) or followed standard defined steps during insertion (Group 2, n = 100).
UNASSIGNED: Almost double the patients had occurrence of thrombophlebitis in Group 1 (p = 0.02). No difference observed between catheter needle size and infection rates (p = 0.3). Infection rate increased significantly if second attempt is taken for insertion. The time required to insert catheter following CDC recommended protocol is less than as by standard surgical complete asepsis cleaning protocol (86.03 vs 109.40 s) (p = 0.001). Study also observed that insertion at wrist joint leads to higher incidence of thrombophlebitis. During 0-24 h, 6% (12) insertions turned positive followed by a dip during 25-48 h, 2% (5) insertions. 80% (159) insertions did not develop thrombophlebitis at the end of 72 h.
UNASSIGNED: It is thus amply demonstrated that meticulous adherence to insertion procedure with asepsis plays an important role in decreasing intravascular catheter associated morbidity. Other parameters like needle gauge, sites of insertion, have little bearing. The time required in following standard aseptic technique is significantly more but keeping in view the benefit to the patient it is highly recommended.
UNASSIGNED: Patients were randomized and catheter was inserted as recommended by CDC guideline (Group 1, n = 100) or followed standard defined steps during insertion (Group 2, n = 100).
UNASSIGNED: Almost double the patients had occurrence of thrombophlebitis in Group 1 (p = 0.02). No difference observed between catheter needle size and infection rates (p = 0.3). Infection rate increased significantly if second attempt is taken for insertion. The time required to insert catheter following CDC recommended protocol is less than as by standard surgical complete asepsis cleaning protocol (86.03 vs 109.40 s) (p = 0.001). Study also observed that insertion at wrist joint leads to higher incidence of thrombophlebitis. During 0-24 h, 6% (12) insertions turned positive followed by a dip during 25-48 h, 2% (5) insertions. 80% (159) insertions did not develop thrombophlebitis at the end of 72 h.
UNASSIGNED: It is thus amply demonstrated that meticulous adherence to insertion procedure with asepsis plays an important role in decreasing intravascular catheter associated morbidity. Other parameters like needle gauge, sites of insertion, have little bearing. The time required in following standard aseptic technique is significantly more but keeping in view the benefit to the patient it is highly recommended.
摘要：
未经批准：全球有数百万在医疗设施中入院的患者需要插入外周血管内导管以进行静脉内药物或液体给药。然而,如果在插入过程中没有遵循适当的预防措施，它会导致严重的发病率。这项研究旨在研究推荐的疾病控制和预防中心（CDC）指南对外周血管内导管插入实践的有效性和安全性，以及与所遵循的标准插入方案的比较及其结果。
UNASSIGNED：患者被随机分配，并按照CDC指南的建议插入导管（第1组，n=100）或在插入过程中遵循标准定义的步骤（第2组，n=100）。
未经证实：在第1组中，几乎有两倍的患者发生了血栓性静脉炎（p=0.02）。导管针头大小和感染率之间没有观察到差异（p=0.3）。如果第二次尝试插入，感染率显着增加。按照CDC推荐方案插入导管所需的时间少于标准外科完全无菌清洁方案(86.03vs109.40s)(p=0.001)。研究还观察到，插入腕关节会导致血栓性静脉炎的发生率更高。在0-24小时内，6％（12）插入变为阳性，然后在25-48小时内下降，2%(5)插入。在72小时结束时，80％（159）的插入未发生血栓性静脉炎。
UNASSIGNED：因此，充分证明，在无菌情况下，精心坚持插入程序在降低血管内导管相关发病率方面起着重要作用。其他参数，如针规，插入部位，有点轴承。遵循标准无菌技术所需的时间明显更多，但强烈建议保持对患者的益处。
UNASSIGNED：患者被随机分配，并按照CDC指南的建议插入导管（第1组，n=100）或在插入过程中遵循标准定义的步骤（第2组，n=100）。
未经证实：在第1组中，几乎有两倍的患者发生了血栓性静脉炎（p=0.02）。导管针头大小和感染率之间没有观察到差异（p=0.3）。如果第二次尝试插入，感染率显着增加。按照CDC推荐方案插入导管所需的时间少于标准外科完全无菌清洁方案(86.03vs109.40s)(p=0.001)。研究还观察到，插入腕关节会导致血栓性静脉炎的发生率更高。在0-24小时内，6％（12）插入变为阳性，然后在25-48小时内下降，2%(5)插入。在72小时结束时，80％（159）的插入未发生血栓性静脉炎。
UNASSIGNED：因此，充分证明，在无菌情况下，精心坚持插入程序在降低血管内导管相关发病率方面起着重要作用。其他参数，如针规，插入部位，有点轴承。遵循标准无菌技术所需的时间明显更多，但强烈建议保持对患者的益处。
