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Abstract：
UNASSIGNED: Deliberate self-poisoning (DSP) is one of the leading causes of mortality and morbidity, with rodenticides being common compounds used by many victims. However, comprehensive data regarding the spectrum and outcome of rodenticide poisoning is scant.
UNASSIGNED: This retrospective study was conducted in the Emergency Department (ED) of a large tertiary care hospital in South India between January 2017 and December 2018. All patients with deliberate consumption of rodenticides were included in the analysis.
UNASSIGNED: During the study period, 1802 patients presented with DSP, among which 145 (8%) consumed rodenticide compounds. The mean (SD) age was 27.9 (10.7) years. Young adults (16-30 years) comprised 73% (106/145) of the study population. The majority (87%) were triaged as priority 2, while 10% were triaged as priority 1. Common rodenticide compounds consumed were yellow phosphorous (57%: 82/145), coumarins (12%: 17/145), zinc phosphide (19%: 27/145), and aluminum phosphide (1%: 1/145). A significant proportion of patients (18.6%) were under the influence of alcohol. Among the 73 males, 25 (34.2%) gave a history of co-consumption of alcohol. There was a history of previous DSP attempts in 6%. The majority (68%) of the patients were discharged alive from the hospital, and the in-hospital mortality rate was 9%. Age >30 years (adjusted OR: 2.2; 95% CI: 1.00-5.05; p value: 0.04) was an independent predictor of poor outcome.
UNASSIGNED: Rodenticide compound consumption for DSP is prevalent in young adults and is associated with significant mortality, especially with yellow phosphorous poisoning. The current trend in our country of the increasing use of highly fatal phosphorous compounds over the innocuous coumarin derivatives is a cause of grave concern.
UNASSIGNED: This retrospective study was conducted in the Emergency Department (ED) of a large tertiary care hospital in South India between January 2017 and December 2018. All patients with deliberate consumption of rodenticides were included in the analysis.
UNASSIGNED: During the study period, 1802 patients presented with DSP, among which 145 (8%) consumed rodenticide compounds. The mean (SD) age was 27.9 (10.7) years. Young adults (16-30 years) comprised 73% (106/145) of the study population. The majority (87%) were triaged as priority 2, while 10% were triaged as priority 1. Common rodenticide compounds consumed were yellow phosphorous (57%: 82/145), coumarins (12%: 17/145), zinc phosphide (19%: 27/145), and aluminum phosphide (1%: 1/145). A significant proportion of patients (18.6%) were under the influence of alcohol. Among the 73 males, 25 (34.2%) gave a history of co-consumption of alcohol. There was a history of previous DSP attempts in 6%. The majority (68%) of the patients were discharged alive from the hospital, and the in-hospital mortality rate was 9%. Age >30 years (adjusted OR: 2.2; 95% CI: 1.00-5.05; p value: 0.04) was an independent predictor of poor outcome.
UNASSIGNED: Rodenticide compound consumption for DSP is prevalent in young adults and is associated with significant mortality, especially with yellow phosphorous poisoning. The current trend in our country of the increasing use of highly fatal phosphorous compounds over the innocuous coumarin derivatives is a cause of grave concern.
摘要：
未经证实：故意自我中毒（DSP）是导致死亡和发病的主要原因之一，杀鼠剂是许多受害者使用的常见化合物。然而,关于杀鼠剂中毒的频谱和结果的全面数据很少。
UNASSIGNED：这项回顾性研究于2017年1月至2018年12月在印度南部一家大型三级保健医院的急诊科（ED）进行。所有故意食用杀鼠剂的患者都包括在分析中。
未经评估：在研究期间，1802名患者接受DSP治疗，其中145种(8%)食用杀鼠剂化合物。平均（SD）年龄为27.9（10.7）岁。年轻人（16-30岁）占研究人群的73％（106/145）。大多数（87％）被分类为优先级2，而10％被分类为优先级1。消耗的常见杀鼠剂化合物是黄磷(57%:82/145)，香豆素（12%：17/145），磷化锌（19%：27/145），和磷化铝(1%:1/145)。很大比例的患者（18.6％）受到酒精的影响。在73名男性中，25人(34.2%)有共同饮酒史。以前有6%的DSP尝试历史。大部分(68%)的病人是活活出院,住院死亡率为9%。年龄>30岁(校正后OR:2.2;95%CI:1.00-5.05;p值:0.04)是不良结局的独立预测因子。
未经评估：DSP的杀鼠剂复合消费在年轻人中普遍存在，并与显著的死亡率相关，尤其是黄磷中毒.目前在我国越来越多地使用高致命性的磷化合物而不是无害的香豆素衍生物的趋势是引起严重关注的原因。
UNASSIGNED：这项回顾性研究于2017年1月至2018年12月在印度南部一家大型三级保健医院的急诊科（ED）进行。所有故意食用杀鼠剂的患者都包括在分析中。
未经评估：在研究期间，1802名患者接受DSP治疗，其中145种(8%)食用杀鼠剂化合物。平均（SD）年龄为27.9（10.7）岁。年轻人（16-30岁）占研究人群的73％（106/145）。大多数（87％）被分类为优先级2，而10％被分类为优先级1。消耗的常见杀鼠剂化合物是黄磷(57%:82/145)，香豆素（12%：17/145），磷化锌（19%：27/145），和磷化铝(1%:1/145)。很大比例的患者（18.6％）受到酒精的影响。在73名男性中，25人(34.2%)有共同饮酒史。以前有6%的DSP尝试历史。大部分(68%)的病人是活活出院,住院死亡率为9%。年龄>30岁(校正后OR:2.2;95%CI:1.00-5.05;p值:0.04)是不良结局的独立预测因子。
未经评估：DSP的杀鼠剂复合消费在年轻人中普遍存在，并与显著的死亡率相关，尤其是黄磷中毒.目前在我国越来越多地使用高致命性的磷化合物而不是无害的香豆素衍生物的趋势是引起严重关注的原因。
