Data for patients with ICH between the years of 2015 and 2018 were extracted from the Nationwide Inpatient Sample and stratified based on the diagnosis of TC.
Our results showed that the incidence rate of TC in ICH discharges was 0.27% (95% confidence interval [CI] 0.24-0.31). The mean age of patients with ICH developing TC was 66.28 years ± 17.11. There were significantly more women in the TC group, with an odds ratio (OR) of 3.65 (95% CI 2.63-5.05). Acute myocardial infarction (OR 7.91, 95% CI 5.80-10.80) was significantly higher in the TC group. The mortality rate of patients with ICH who had TC was significantly higher (33.48%, p < 0.0001). Length of stay (mean days; 15.72 ± 13.56 vs. 9.56 ± 14.10, p < 0.0001) significantly increased in patients with ICH who had TC. Patients with intraventricular ICH (OR 2.46, 95% CI 1.88-3.22) had the highest odds of TC.
Takotsubo cardiomyopathy is associated with a higher mortality, longer hospitalization period, and more acute myocardial infarctions in patients with ICH. It is illustrated that intraventricular ICH is associated with higher odds of TC.
方法:从全国住院患者样本中提取2015年至2018年的ICH患者数据,并根据TC的诊断进行分层。
结果:我们的结果表明,ICH出院中TC的发生率为0.27%(95%置信区间[CI]0.24-0.31)。发生TC的ICH患者的平均年龄为66.28岁±17.11岁。TC组中有更多的女性,比值比(OR)为3.65(95%CI2.63-5.05)。急性心肌梗死(OR7.91,95%CI5.80-10.80)明显高于TC组。有TC的ICH患者的死亡率明显较高(33.48%,p<0.0001)。住院时间(平均天数;15.72±13.56vs.9.56±14.10,p<0.0001)在患有TC的ICH患者中显着增加。脑室内ICH患者(OR2.46,95%CI1.88-3.22)的TC几率最高。
结论:Takotsubo心肌病与较高的死亡率相关,住院时间更长,ICH患者的急性心肌梗塞更多。说明心室内ICH与TC的较高几率相关。