PDF(Pubmed)
Abstract：
A 38 year old woman presented with burns totaling 45 % total body surface area, following an explosion resulting from manufacturing cannabis wax. Initial debridement, was delayed to hospital day 7 due to hemodynamic instability. Over the course of her, hospitalization, she required multiple debridements and grafting to her lower, extremities; grafted tissue never survived longer than 72 h. Her bilateral lower, extremities began to exhibit visible mold growth. She underwent repeated, debridements down to vitalized tissue only for recurrent necrosis and mold growth to, occur. She underwent serial amputations eventually reaching the level of her midthigh, At this point her clinical condition deteriorated further resulting in multiorgan failure., Ultimately family made the decision to remove her from life support, and she expired, within a few hours. Postmortem analysis identified Rhizopus spp, Fusarium spp, and, Geotrichum candidum. Mucormycosis species are a frequent infector of Cannabis, sativa, which our patient was working with in the inciting explosion. Cutaneous, mucormycosis is a documented but rare manifestation. We propose that the patient\'s, relatively young age, severity of burns, and exposure to cannabis plants resulted in this, unusual presentation.
摘要：
一名38岁的女性出现烧伤，总面积达45％，在制造大麻蜡发生爆炸后。初始清创术，由于血流动力学不稳定，延迟至医院第7天。在她的过程中，住院治疗,她需要多次清创和移植到她的下部，四肢；移植组织从未存活超过72小时。她的双侧下部，四肢开始表现出可见的霉菌生长。她经历了反复，清创术仅用于复发性坏死和霉菌生长，发生。她接受了连续截肢手术，最终达到了大腿中部的水平，此时，她的临床状况进一步恶化，导致多器官衰竭。,最终，家人决定将她从生命支持系统中删除，她过期了,在几个小时内。验尸分析确定根霉属，镰刀菌属,and,念珠菌。毛霉菌病是大麻的常见感染者，sativa,我们的病人在煽动爆炸中与之合作。皮肤,毛霉菌病是有记载但罕见的表现。我们建议病人,相对年轻的年龄，烧伤的严重程度，接触大麻植物导致了这种情况，不寻常的介绍。
