关键词: Libya Seroprevalence TOSV Yefran

Mesh : Antibodies, Viral Female Humans Immunoglobulin G Libya / epidemiology Male Meningoencephalitis / epidemiology Sandfly fever Naples virus Seroepidemiologic Studies

来  源:   DOI:10.4103/0972-9062.335728

Abstract:
OBJECTIVE: In Mediterranean countries, infection of Toscana virus is a public health problem during the summer season, related to sandflies activity; it may cause aseptic meningitis and mild meningoencephalitis. We investigated the presence of antibodies (IgG) against the Toscana virus in the sera of individuals living in the area of Yafran, Libya.
METHODS: During the period from December 2013 to February 2014, a total of 232 sera samples were collected from Yefran hospital. Demographic information of participants collected in a questionnaire; samples were analyzed by the serological method of enzyme-linked immunoassays specific for Toscana IgG antibodies.
RESULTS: Seroprevalence of IgG antibodies among samples was 25% (n = 232). Seroprevalence varied among genders, age groups. The differences were not statically significant.
CONCLUSIONS: Our findings indicate and confirm local circulation of the Toscana virus. It also indicates that TOSV infection is neglected, and needs to be considered as one of the causes of meningitis or meningoencephalitis.
摘要:
目标:在地中海国家,托斯卡纳病毒感染是夏季的公共卫生问题,与沙蝇活动有关;它可能引起无菌性脑膜炎和轻度脑膜脑炎。我们调查了生活在Yafran地区的个体血清中针对Toscana病毒的抗体(IgG)的存在,利比亚。
方法:在2013年12月至2014年2月期间,从Yefran医院收集了232份血清样本。问卷中收集的参与者的人口统计信息;通过对ToscanaIgG抗体具有特异性的酶联免疫测定的血清学方法分析样品。
结果:样品中IgG抗体的血清阳性率为25%(n=232)。血清阳性率因性别而异,年龄组。差异不是静态显著的。
结论:我们的发现表明并证实了Toscana病毒的局部流行。这也表明TOSV感染被忽视了,并且需要被认为是脑膜炎或脑膜脑炎的原因之一。
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