关键词: ACE-R, Addenbrooke's Cognitive Examination-Revised ANOVA, analysis of variance BDNF, brain-derived neurotropic factor Dietary supplements Elderly Ex, exercise-only group Ex + Nt, exercise plus nutrition group GDS-15, Geriatric Depression Scale 15 MMSE, Mini-Mental State Examination Memory Motor function SMI, skeletal muscle mass index SPI, soy protein isolate

来  源:   DOI:10.1016/j.conctc.2022.100998   PDF(Pubmed)

Abstract:
UNASSIGNED: Soy peptide, when consumed as a functional food, has been reported to improve cognitive function. This study aimed to verify the combined effect of soy peptide supplementation and exercise on cognitive function among community-dwelling older adults in Japan.
UNASSIGNED: In this population-based, non-blinded randomized controlled trial, 72 community-dwelling older adults who were independent in activities of daily living were randomly assigned to an \"exercise plus nutrition\" program (Ex + Nt group, n = 36) or an exercise program (Ex group, n = 36). For 3 months, both groups participated in an exercise and cognitive training regimen once per week, with the Ex + Nt group receiving soy supplementation once per week. Pre- and post-intervention measurements included grip strength, gait speed, skeletal muscle mass index, and scores on Addenbrooke\'s Cognitive Examination-Revised, trail-making test A, and the Geriatric Depression Scale. Participant enrollment for this study started in January 2019 and ended in April 2019.
UNASSIGNED: Exercise training increased the skeletal muscle mass index by 2.0% and 3.0% in the Ex + Nt and Ex groups, respectively. The Ex + Nt group exhibited a significant 0.3-point increase in the memory score.
UNASSIGNED: A 3-month exercise program combined with soy peptide supplementation may be effective in improving both motor and memory function in community-dwelling older adults.
摘要:
未经批准:大豆肽,当作为功能性食物食用时,据报道可以改善认知功能。本研究旨在验证大豆肽补充剂和运动对日本社区老年人认知功能的综合影响。
未经评估:在这种基于人口的情况下,非盲随机对照试验,72名在日常生活活动中独立的社区老年人被随机分配到“运动加营养”计划(Ex+Nt组,n=36)或锻炼计划(Ex组,n=36)。三个月,两组每周参加一次运动和认知训练方案,Ex+Nt组每周接受一次大豆补充剂。干预前和干预后的测量包括握力,步态速度,骨骼肌质量指数,和Addenbrooke认知考试的分数-修订,跟踪测试A,和老年抑郁量表。这项研究的参与者注册于2019年1月开始,并于2019年4月结束。
未经评估:运动训练使Ex+Nt和Ex组的骨骼肌质量指数分别增加了2.0%和3.0%,分别。Ex+Nt组表现出记忆评分的显著0.3点增加。
UNASSIGNED:3个月的锻炼计划结合大豆肽补充剂可能有效改善社区居住的老年人的运动和记忆功能。
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