PDF(Pubmed)
Abstract：
UNASSIGNED: To determine the frequency of skeletal dysplasia in children with short stature presenting to the endocrine clinic of a tertiary care hospital.
UNASSIGNED: This descriptive cross-sectional study was performed in the Outpatient Department of Endocrinology of National Institute of Child Health, Karachi, for 6 months of duration. A total of 200 children coming to endocrine OPD of NICH of either gender, having the age less than 14 years and height more than -2.5 SD below the mean (<3rd percentile), and growth failure (<4 cm/yr) were enrolled. A complete general physical examination including height, weight, fronto-occipital circumference (FOC), arm span, and U/L (upper/lower) segment ratio (using SI units and SDS) was performed.
UNASSIGNED: Out of 200 children with short stature, skeletal dysplasia was diagnosed in 23 (11.5%) children with the mean age of 4.7 (±3.7) years. Proportion of skeletal dysplasia among short stature was high in females. Out of 75 girls, skeletal dysplasia was diagnosed in 10 (13.3%) girls, while out of 125 boys, skeletal dysplasia was diagnosed in 13 (10.4%) boys, whereas when we see proportion among skeletal dysplasia out of 23 children of skeletal dysplasia, 13 (56.5%) were boys, while 10 (43.5%) were girls.
UNASSIGNED: In this study, skeletal dysplasia was diagnosed in 11.5% children with short stature with the mean age of 4.7 years. It is concluded that the frequency of skeletal dysplasia in this institute is fairly high.
UNASSIGNED: This descriptive cross-sectional study was performed in the Outpatient Department of Endocrinology of National Institute of Child Health, Karachi, for 6 months of duration. A total of 200 children coming to endocrine OPD of NICH of either gender, having the age less than 14 years and height more than -2.5 SD below the mean (<3rd percentile), and growth failure (<4 cm/yr) were enrolled. A complete general physical examination including height, weight, fronto-occipital circumference (FOC), arm span, and U/L (upper/lower) segment ratio (using SI units and SDS) was performed.
UNASSIGNED: Out of 200 children with short stature, skeletal dysplasia was diagnosed in 23 (11.5%) children with the mean age of 4.7 (±3.7) years. Proportion of skeletal dysplasia among short stature was high in females. Out of 75 girls, skeletal dysplasia was diagnosed in 10 (13.3%) girls, while out of 125 boys, skeletal dysplasia was diagnosed in 13 (10.4%) boys, whereas when we see proportion among skeletal dysplasia out of 23 children of skeletal dysplasia, 13 (56.5%) were boys, while 10 (43.5%) were girls.
UNASSIGNED: In this study, skeletal dysplasia was diagnosed in 11.5% children with short stature with the mean age of 4.7 years. It is concluded that the frequency of skeletal dysplasia in this institute is fairly high.
摘要：
UNASSIGNED：旨在确定到三级保健医院内分泌诊所就诊的身材矮小儿童骨骼发育不良的频率。
UNASSIGNED：这项描述性横断面研究是在美国国家儿童健康研究所内分泌学门诊进行的，卡拉奇,为期6个月。共有200名儿童来到NICH的内分泌OPD，年龄小于14岁，身高低于平均值-2.5SD以上（<第3百分位数），和生长失败（<4cm/年）。包括身高在内的全面体检，体重,额枕骨围（FOC），臂跨度,和U/L(上/下)片段比(使用SI单位和SDS)进行。
未经评估：在200名身材矮小的儿童中，23例(11.5%)儿童诊断为骨骼发育不良,平均年龄为4.7(±3.7)岁.女性身材矮小者中骨骼发育不良的比例很高。在75个女孩中，10名(13.3%)女孩被诊断出骨骼发育不良，而在125个男孩中，13名(10.4%)男孩被诊断出骨骼发育不良，而当我们看到23名骨骼发育不良儿童中骨骼发育不良的比例时，13（56.5％）是男孩，10名(43.5%)是女孩。
未经批准：在这项研究中，11.5%的身材矮小儿童诊断为骨骼发育不良,平均年龄为4.7岁.结论是该研究所骨骼发育不良的频率相当高。
UNASSIGNED：这项描述性横断面研究是在美国国家儿童健康研究所内分泌学门诊进行的，卡拉奇,为期6个月。共有200名儿童来到NICH的内分泌OPD，年龄小于14岁，身高低于平均值-2.5SD以上（<第3百分位数），和生长失败（<4cm/年）。包括身高在内的全面体检，体重,额枕骨围（FOC），臂跨度,和U/L(上/下)片段比(使用SI单位和SDS)进行。
未经评估：在200名身材矮小的儿童中，23例(11.5%)儿童诊断为骨骼发育不良,平均年龄为4.7(±3.7)岁.女性身材矮小者中骨骼发育不良的比例很高。在75个女孩中，10名(13.3%)女孩被诊断出骨骼发育不良，而在125个男孩中，13名(10.4%)男孩被诊断出骨骼发育不良，而当我们看到23名骨骼发育不良儿童中骨骼发育不良的比例时，13（56.5％）是男孩，10名(43.5%)是女孩。
未经批准：在这项研究中，11.5%的身材矮小儿童诊断为骨骼发育不良,平均年龄为4.7岁.结论是该研究所骨骼发育不良的频率相当高。
