Abstract：
OBJECTIVE: Colombia is a country with a high prevalence of hypothyroidism, approximately 18.5% compared to the rest of Latin American countries, which is estimated at 10%. That is why in the ophthalmology consultation we find a large proportion of patients with this disease and who also present symptoms of dry eye. When conducting a search in the medical literature, most publications refer to the clinical presentation of dry eye in hyperthyroidism, which is why the main objective of this study is to evaluate tear function tests in the diagnosis of dry eye in patients with hypothyroidism.
METHODS: This is an observational, cross-sectional study carried out in the period between May and December 2019 in the ocular surface unit of the Ophthalmic Technology Center (CTO) in Bogotá. The tests of: OSDI test (Ocular Surface Disease Index), Schirmer type I, tear meniscus height, NiBUT, Osmolarity, Ferning test, Lisamine Green test of 59 patients with Dry Eye Disease (DED) and history of hypothyroidism.
RESULTS: Schirmer type I and NiBUT tests were the parameters that presented the highest percentage of severity, while lissamine green staining and meniscometry showed a tendency to normality.
CONCLUSIONS: The population of this study presents a mixed type dry eye without epithelial cell damage.
METHODS: This is an observational, cross-sectional study carried out in the period between May and December 2019 in the ocular surface unit of the Ophthalmic Technology Center (CTO) in Bogotá. The tests of: OSDI test (Ocular Surface Disease Index), Schirmer type I, tear meniscus height, NiBUT, Osmolarity, Ferning test, Lisamine Green test of 59 patients with Dry Eye Disease (DED) and history of hypothyroidism.
RESULTS: Schirmer type I and NiBUT tests were the parameters that presented the highest percentage of severity, while lissamine green staining and meniscometry showed a tendency to normality.
CONCLUSIONS: The population of this study presents a mixed type dry eye without epithelial cell damage.
摘要：
目的：哥伦比亚是甲状腺功能减退症患病率高的国家，与其他拉丁美洲国家相比，约为18.5%，估计为10%。这就是为什么在眼科咨询中，我们发现患有这种疾病的患者比例很大，并且也存在干眼症状。在医学文献中进行搜索时，大多数出版物都提到了甲状腺功能亢进中干眼的临床表现，这就是为什么这项研究的主要目的是评估泪液功能测试在诊断甲状腺功能减退患者干眼中的作用。
方法：这是一个观察性的，2019年5月至12月在波哥大眼科技术中心（CTO）眼表单元进行的横断面研究。测试：OSDI测试（眼表疾病指数），SchirmerI型,撕裂半月板高度，NIBUT,渗透压,轮渡试验,59例干眼症（DED）和甲状腺功能减退症病史的LisamineGreen试验。
结果：SchirmerI型和NiBUT测试是表示严重程度百分比最高的参数，而lissamine绿色染色和半月板显示出正常趋势。
结论：本研究人群表现为无上皮细胞损伤的混合型干眼。
方法：这是一个观察性的，2019年5月至12月在波哥大眼科技术中心（CTO）眼表单元进行的横断面研究。测试：OSDI测试（眼表疾病指数），SchirmerI型,撕裂半月板高度，NIBUT,渗透压,轮渡试验,59例干眼症（DED）和甲状腺功能减退症病史的LisamineGreen试验。
结果：SchirmerI型和NiBUT测试是表示严重程度百分比最高的参数，而lissamine绿色染色和半月板显示出正常趋势。
结论：本研究人群表现为无上皮细胞损伤的混合型干眼。
