Mesh : Blood Cell Count Case-Control Studies Female Humans Lymphocyte Count Pregnancy Retrospective Studies Surgical Wound Infection

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Abstract:
BACKGROUND: Cesarean delivery (CD) is the most frequently performed surgery. Surgical site infection (SSI) is a common complication after CD.
OBJECTIVE: To evaluate the role of complete blood count parameters in predicting the development of SSI after CD.
METHODS: Patients who were hospitalized because of SSI after CD were included in the SSI group (n = 48). A control group (n = 45) was formed with healthy postpartum women who had also undergone CD. Preoperative and postoperative hemoglobin (Hb), white blood cell count (WBC), neutrophil count, lymphocyte count, platelet count (PLT), neutrophil-to-lymphocyte ratio (NLR), platelet-lymphocyte ratio (PLR), mean platelet volume (MPV), and platelet-large cell ratio (P-LCR) were recorded.
RESULTS: WBC, neutrophil count, and NLR levels increased while Hb, PLT, and lymphocyte count levels decreased after CD in both the SSI and control groups. PLR increased after CD in the SSI group but remained stable in the control group. However, the difference in PLR could not predict SSI after CD.
CONCLUSIONS: Complete blood count parameters were not useful to predict SSI after CD. Larger prospective studies are needed.
摘要:
背景:剖宫产(CD)是最常见的手术。手术部位感染(SSI)是CD术后常见的并发症。
目的:评估全血细胞计数参数在预测CD后SSI发展中的作用。
方法:将因CD后SSI住院的患者纳入SSI组(n=48)。对照组(n=45)由健康的产后妇女组成,她们也经历了CD。术前、术后血红蛋白(Hb),白细胞计数(WBC),中性粒细胞计数,淋巴细胞计数,血小板计数(PLT),中性粒细胞与淋巴细胞比率(NLR),血小板-淋巴细胞比率(PLR),平均血小板体积(MPV),并记录血小板-大细胞比率(P-LCR)。
结果:WBC,中性粒细胞计数,和NLR水平增加,而Hb,PLT,在SSI组和对照组中,CD后淋巴细胞计数水平均下降。SSI组CD后PLR升高,对照组则保持稳定。然而,PLR的差异不能预测CD后的SSI。
结论:全血细胞计数参数不能用于预测CD后的SSI。需要更大的前瞻性研究。
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