PDF(Pubmed)
Abstract：
Within the specialties of infectious diseases and dermatology, few rashes involve the palms and soles. The syphilitic rash has a pathognomonic association with these body surfaces and signals physicians to investigate this disease. However, the distinct presentations and symptoms associated with syphilis and the various stages of the disease make it diagnostically challenging. We herein report a rather intricate and unusual case of a patient who presented with a new-onset headache and blurred vision and a two-month history of diffuse pruritic maculopapular rash sparing the palms and soles. Several physicians had not established a diagnosis in the outpatient setting. Inpatient workup eventually revealed that the patient was suffering from secondary syphilis with neurological and ocular involvement. Management included a prolonged course of intravenous penicillin G leading to a complete recovery. We share images of the skin findings and the details of the intricate workup and hospital course, as well as a review of the literature.
摘要：
在传染病和皮肤病学的专业范围内，很少有皮疹涉及手掌和脚底。梅毒性皮疹与这些身体表面具有病理性关联，并向医生发出信号以研究这种疾病。然而,与梅毒相关的独特表现和症状以及疾病的各个阶段使其在诊断上具有挑战性。我们在此报告了一个相当复杂且不寻常的病例，该患者出现了新发作的头痛和视力模糊，并且有两个月的弥漫性瘙痒斑丘疹病史，手掌和脚底很少。几位医生尚未在门诊环境中确定诊断。住院检查最终发现该患者患有继发性梅毒，并伴有神经和眼部受累。管理包括延长静脉注射青霉素G的疗程，从而完全康复。我们分享皮肤发现的图像以及复杂的检查和医院课程的细节，以及文献综述。
