Abstract:
The long-term treatment of congestive heart failure (CHF) in children includes digoxin, diuretics and afterload reduction with angiotensin-converting enzyme (ACE) inhibitors. In spite of the wide use of these drugs being the standard, yet, pediatric heart failure (PHF) continued to be an important cause of morbidity and mortality in childhood. Introduction of new drugs has elevated the level of tolerance of these patients and played a role in delaying their urgent need to have heart transplant or Mechanical circulatory support (MCS). Together with a patient by patient tailored combination of different diuretics. We aim to present and discuss these new drugs and the combinations of regular drugs to reach the best outcome, as well as the consensus of our pediatric heart failure working group in Egypt.
摘要:
儿童充血性心力衰竭(CHF)的长期治疗包括地高辛,使用血管紧张素转换酶(ACE)抑制剂的利尿剂和后负荷减少。尽管这些药物的广泛使用是标准,然而,小儿心力衰竭(PHF)仍然是儿童发病和死亡的重要原因.新药的引入提高了这些患者的耐受性水平,并在延迟他们迫切需要进行心脏移植或机械循环支持(MCS)方面发挥了作用。与患者一起由患者量身定制不同利尿剂的组合。我们的目标是提出和讨论这些新药和常规药物的组合,以达到最佳的结果,以及我们在埃及的小儿心力衰竭工作组的共识。