关键词: Acetilcholinesterase Agrochemical Aquatic environment Biomarkers Fish life stages Zebrafish

Mesh : Animals Fishes Glycine / analogs & derivatives toxicity Herbicides / analysis toxicity Wastewater Water Pollutants, Chemical / toxicity Glyphosate

来  源:   DOI:10.1016/j.aquatox.2022.106281

Abstract:
The use of agrochemicals has grown in recent years following the increase in agricultural productivity, to eliminate weeds that can compromise crop yields. The intensive use of these products combined with the lack of treatment of agricultural wastewater is causing contamination of the natural environments, especially the aquatics. Glyphosate [N-(phosphonomethyl) glycine] is the most commonly used herbicide in agriculture worldwide. Studies have shown that this compound is toxic to a variety of fish species at the concentrations of environmental relevance. Glyphosate-based herbicides can affect fish biochemical, physiological, endocrine, and behavioral pathways. Changes in behaviors such as foraging, escaping from predators, and courtship can compromise the survival of species and even communities. The behavior patterns of fish has been shown to be a sensitive tool for risk assessment. In this sense, this review summarizes and discusses the toxic effects of glyphosate and its formulations on the behavior of fish in different life stages. Additionally, behavioral impairments were associated with other negative effects of glyphosate such as energy imbalance, stress responses, AChE inhibition, and physiological and endocrine disturbances, which are evidenced and described in the literature. Graphical abstract.
摘要:
近年来,随着农业生产力的提高,农用化学品的使用有所增加,消除可能损害作物产量的杂草。这些产品的大量使用加上缺乏对农业废水的处理,造成了自然环境的污染,尤其是水上运动.草甘膦[N-(膦酰基甲基)甘氨酸]是全世界农业中最常用的除草剂。研究表明,该化合物在与环境相关的浓度下对各种鱼类有毒。草甘膦除草剂可以影响鱼类生化,生理,内分泌,和行为路径。行为的变化,如觅食,逃离捕食者,求爱会危及物种甚至社区的生存。鱼类的行为模式已被证明是风险评估的敏感工具。在这个意义上,本文总结并讨论了草甘膦及其制剂对不同生命阶段鱼类行为的毒性作用。此外,行为障碍与草甘膦的其他负面影响有关,如能量失衡,应激反应,AChE抑制,生理和内分泌紊乱,这在文献中得到了证明和描述。图形抽象。
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