Abstract：
OBJECTIVE: To analyze the relationship between tear meniscus dimensions and higher-order aberrations (HOAs) in patients with lacrimal passage obstruction using anterior segment optical coherence tomography (AS-OCT).
METHODS: This study was a retrospective observational study of 71 eyes of 49 patients with lacrimal passage obstruction. These patients received sheath-guided dacryoendoscopic probing and bicanalicular intubation (SG-BCI) at Toyama University Hospital between August 2020 and October 2021. Using AS-OCT, tear meniscus height (TMH), tear meniscus area (TMA), and total corneal HOAs values were measured before and after surgery.
RESULTS: Surgical success was achieved in 69 eyes (97.1%). At the final observation, 62 eyes showed lacrimal patency (89.8%). The preoperative TMH, TMA, and HOAs values were 1.55 ± 0.96 mm, 0.11 ± 0.14 mm2, and 0.37 ± 0.27 µm, respectively, and the final postoperative TMH, TMA, and HOAs values were 0.97 ± 0.74 mm (p < 0.0001), 0.06 ± 0.11 mm2 (p = 0.02), and 0.29 ± 0.16 µm (p = 0.001), respectively. The results showed a significant improvement. The changes in HOAs before and after surgery were positively correlated with the changes in TMH (r = 0.3476, p = 0.0241) and TMA (r = 0.3653, p = 0.0174).
CONCLUSIONS: SG-BCI for lacrimal passage obstruction resulted in a significant decrease in measured HOAs. The decrease in HOAs was correlated with decreases in tear meniscus dimensions.
METHODS: This study was a retrospective observational study of 71 eyes of 49 patients with lacrimal passage obstruction. These patients received sheath-guided dacryoendoscopic probing and bicanalicular intubation (SG-BCI) at Toyama University Hospital between August 2020 and October 2021. Using AS-OCT, tear meniscus height (TMH), tear meniscus area (TMA), and total corneal HOAs values were measured before and after surgery.
RESULTS: Surgical success was achieved in 69 eyes (97.1%). At the final observation, 62 eyes showed lacrimal patency (89.8%). The preoperative TMH, TMA, and HOAs values were 1.55 ± 0.96 mm, 0.11 ± 0.14 mm2, and 0.37 ± 0.27 µm, respectively, and the final postoperative TMH, TMA, and HOAs values were 0.97 ± 0.74 mm (p < 0.0001), 0.06 ± 0.11 mm2 (p = 0.02), and 0.29 ± 0.16 µm (p = 0.001), respectively. The results showed a significant improvement. The changes in HOAs before and after surgery were positively correlated with the changes in TMH (r = 0.3476, p = 0.0241) and TMA (r = 0.3653, p = 0.0174).
CONCLUSIONS: SG-BCI for lacrimal passage obstruction resulted in a significant decrease in measured HOAs. The decrease in HOAs was correlated with decreases in tear meniscus dimensions.
摘要：
目的：使用眼前节光学相干断层扫描（AS-OCT）分析泪道阻塞患者泪液半月板尺寸与高阶像差（HOAs）之间的关系。
方法：本研究是49例泪道阻塞患者71只眼的回顾性观察研究。这些患者于2020年8月至2021年10月在富山大学医院接受了鞘管引导下的泪镜探查和双管插管（SG-BCI）。使用AS-OCT,撕裂弯月面高度（TMH），泪液半月板面积（TMA），手术前后测量角膜总HOA值。
结果：69眼（97.1%）手术成功率。在最后的观察中,62只眼泪道通畅(89.8%)。术前TMH,TMA,HOAs值为1.55±0.96mm，0.11±0.14mm2和0.37±0.27µm，分别,和最后的术后TMH，TMA,HOAs值为0.97±0.74mm（p<0.0001），0.06±0.11mm2(p=0.02),和0.29±0.16µm(p=0.001)，分别。结果显示了显著的改善。手术前后HOA的变化与TMH(r=0.3476,p=0.0241)和TMA(r=0.3653,p=0.0174)的变化呈正相关。
结论：SG-BCI治疗泪道阻塞导致测得的HOA显著降低。HOA的减少与泪液弯月面尺寸的减少相关。
方法：本研究是49例泪道阻塞患者71只眼的回顾性观察研究。这些患者于2020年8月至2021年10月在富山大学医院接受了鞘管引导下的泪镜探查和双管插管（SG-BCI）。使用AS-OCT,撕裂弯月面高度（TMH），泪液半月板面积（TMA），手术前后测量角膜总HOA值。
结果：69眼（97.1%）手术成功率。在最后的观察中,62只眼泪道通畅(89.8%)。术前TMH,TMA,HOAs值为1.55±0.96mm，0.11±0.14mm2和0.37±0.27µm，分别,和最后的术后TMH，TMA,HOAs值为0.97±0.74mm（p<0.0001），0.06±0.11mm2(p=0.02),和0.29±0.16µm(p=0.001)，分别。结果显示了显著的改善。手术前后HOA的变化与TMH(r=0.3476,p=0.0241)和TMA(r=0.3653,p=0.0174)的变化呈正相关。
结论：SG-BCI治疗泪道阻塞导致测得的HOA显著降低。HOA的减少与泪液弯月面尺寸的减少相关。
