PDF(Pubmed)
Abstract：
UNASSIGNED: At present, the conclusions about the impact of hypertensive disorders of pregnancy (HDP) on the clinical outcomes of preterm infants are inconsistent. This study used the propensity score matching (PSM) analysis to evaluate the effect of HDP on clinical outcomes of extremely preterm or extremely low birth weight (EP/ELBW) infants.
UNASSIGNED: Retrospective analysis was performed on the EP/ELBW infants discharged from 26 tertiary neonatal intensive care units or died during hospitalization from 2008 to 2017, who were divided into HDP group and non-HDP group. The six covariates including sex, gestational age, birth weight, twin or multiple pregnancy, antenatal steroids administration, and conception method were matched through the PSM method at a ratio of 1:1. The survival rate at discharge and the major clinical complications were compared between the two groups.
UNASSIGNED: After matching the six covariates, compared with the non-HDP group, there was no significant difference in the survival rate at discharge (64 vs. 63.2%, p > 0.05), the incidence of bronchopulmonary dysplasia (BPD) or moderate to severe BPD in the HDP group (58.3 vs. 54.9%, p > 0.05; 5.2 vs. 6.2%, p > 0.05). The incidence of periventricular leukomalacia (PVL) in the HDP group was significantly increased (5.7 vs. 1.9%, p < 0.05).
UNASSIGNED: HDP increased the risk of PVL in EP/ELBW infants, but had no significant effect on the survival rate at discharge, or the occurrence of other complications.
UNASSIGNED: Retrospective analysis was performed on the EP/ELBW infants discharged from 26 tertiary neonatal intensive care units or died during hospitalization from 2008 to 2017, who were divided into HDP group and non-HDP group. The six covariates including sex, gestational age, birth weight, twin or multiple pregnancy, antenatal steroids administration, and conception method were matched through the PSM method at a ratio of 1:1. The survival rate at discharge and the major clinical complications were compared between the two groups.
UNASSIGNED: After matching the six covariates, compared with the non-HDP group, there was no significant difference in the survival rate at discharge (64 vs. 63.2%, p > 0.05), the incidence of bronchopulmonary dysplasia (BPD) or moderate to severe BPD in the HDP group (58.3 vs. 54.9%, p > 0.05; 5.2 vs. 6.2%, p > 0.05). The incidence of periventricular leukomalacia (PVL) in the HDP group was significantly increased (5.7 vs. 1.9%, p < 0.05).
UNASSIGNED: HDP increased the risk of PVL in EP/ELBW infants, but had no significant effect on the survival rate at discharge, or the occurrence of other complications.
摘要：
未经批准：目前，关于妊娠期高血压疾病(HDP)对早产儿临床结局的影响的结论不一致.本研究使用倾向评分匹配（PSM）分析来评估HDP对极早产或极低出生体重（EP/ELBW）婴儿临床结局的影响。
UNASSIGNED：回顾性分析2008-2017年26例三级新生儿重症监护病房出院或住院期间死亡的EP/ELBW婴儿，分为HDP组和非HDP组。六个协变量包括性别，胎龄,出生体重,双胎或多胎妊娠,产前类固醇管理，和概念方法通过PSM方法以1：1的比例匹配。比较两组患者出院时的生存率及主要临床并发症。
未经评估：匹配六个协变量后，与非HDP组相比，出院时的生存率没有显着差异（64vs.63.2%,P>0.05)，HDP组支气管肺发育不良（BPD）或中度至重度BPD的发生率（58.3vs.54.9%,p>0.05;5.2vs.6.2%,p>0.05)。HDP组脑室周围白质软化（PVL）的发生率显着增加（5.7vs.1.9%，p<0.05)。
未经证实：HDP增加EP/ELBW婴儿PVL的风险，但对出院时的存活率没有显著影响，或其他并发症的发生。
UNASSIGNED：回顾性分析2008-2017年26例三级新生儿重症监护病房出院或住院期间死亡的EP/ELBW婴儿，分为HDP组和非HDP组。六个协变量包括性别，胎龄,出生体重,双胎或多胎妊娠,产前类固醇管理，和概念方法通过PSM方法以1：1的比例匹配。比较两组患者出院时的生存率及主要临床并发症。
未经评估：匹配六个协变量后，与非HDP组相比，出院时的生存率没有显着差异（64vs.63.2%,P>0.05)，HDP组支气管肺发育不良（BPD）或中度至重度BPD的发生率（58.3vs.54.9%,p>0.05;5.2vs.6.2%,p>0.05)。HDP组脑室周围白质软化（PVL）的发生率显着增加（5.7vs.1.9%，p<0.05)。
未经证实：HDP增加EP/ELBW婴儿PVL的风险，但对出院时的存活率没有显著影响，或其他并发症的发生。
