UNASSIGNED: two hundred samples, were tested on Xpert® HIV-1 Viral Load using 1 ml of plasma in comparison to 600 μl on Abbott Real-time HIV-1 assay. The difference between viral load values was considered significant for Dlog <0.5 log copies/ml.
UNASSIGNED: a good correlation (r=0.985) was noted and confirmed using passing-bablok regression (slope 1.048; 95% CI: 1.036 to 1.069) for 188 samples with samples. A mean difference of 0.0075 log10 copies/ml for a 95% confidence interval (CI) of 0.002 log10 copies/ml to 0.013 log10 copies/ml was obtained. Sensitivity and specificity were respectively 93.6% and 93.5% at the threshold of 1.6 log10 copies/ml and 100% and 99% at the threshold of 3.0 log10 copies/ml.
UNASSIGNED: these results show that Xpert® HIV-1 Viral Load has excellent performance. In Senegal, and can be used for HIV viral load monitoring.
未经评估:200个样本,使用1ml血浆在Xpert®HIV-1病毒载量上进行测试,与600μl的Abbott实时HIV-1测定相比。对于Dlog<0.5log拷贝/ml,病毒载量值之间的差异被认为是显著的。
UNASSIGNED:对于188个样品和样品,使用passing-bablok回归(斜率1.048;95%CI:1.036至1.069)发现并证实了良好的相关性(r=0.985)。对于0.002log10拷贝/ml至0.013log10拷贝/ml的95%置信区间(CI),获得0.0075log10拷贝/ml的平均差。敏感性和特异性在1.6log10拷贝/ml的阈值下分别为93.6%和93.5%,在3.0log10拷贝/ml的阈值下分别为100%和99%。
UNASSIGNED:这些结果表明Xpert®HIV-1ViralLoad具有出色的性能。在塞内加尔,并可用于HIV病毒载量监测。