Abstract：
NEMESIS-3 (Netherlands Mental Health Survey and Incidence Study-3) is a psychiatric epidemiological cohort study of the Dutch general population that replicates and expands on two previous NEMESIS-studies conducted in 1996-1999 and 2007-2018 respectively. The main aims of NEMESIS-3 are to provide up-to-date information on the prevalence, incidence, course and consequences of mental disorders, their risk indicators, and to study the relevant time trends. This paper gives an overview of the objectives and methods of NEMESIS-3, especially of the recently completed first wave, and describes the sample characteristics.
NEMESIS-3 is based on a multistage, stratified random sampling of individuals aged 18-75 years. Face-to-face interviews were laptop computer-assisted and held at the respondent\'s home. A slightly modified Composite International Diagnostic Interview (CIDI) version 3.0 was used to assess both Diagnostic and Statistical Manual of Mental Disorders-IV (DSM-IV) and DSM-5 mental disorders. Two follow-up waves are planned three and six years after baseline.
In the first wave, performed from November 2019 to March 2022, 6194 individuals were interviewed: 1576 respondents before and 4618 respondents during the COVID-19 pandemic. The average interview duration was 91 min and the response rate was 54.6%. The sample consisted of 50.4% women and had a mean age of 47.9 years. The sample was reasonable nationally representative, although some sociodemographic groups were somewhat underrepresented.
Despite the COVID-19 restrictions, we were able to build a large and comprehensive dataset of good quality, permitting us to investigate the latest trends in mental health status, various new topics related to mental health, and the extent to which the pandemic has had an effect on the population\'s mental health.
NEMESIS-3 is based on a multistage, stratified random sampling of individuals aged 18-75 years. Face-to-face interviews were laptop computer-assisted and held at the respondent\'s home. A slightly modified Composite International Diagnostic Interview (CIDI) version 3.0 was used to assess both Diagnostic and Statistical Manual of Mental Disorders-IV (DSM-IV) and DSM-5 mental disorders. Two follow-up waves are planned three and six years after baseline.
In the first wave, performed from November 2019 to March 2022, 6194 individuals were interviewed: 1576 respondents before and 4618 respondents during the COVID-19 pandemic. The average interview duration was 91 min and the response rate was 54.6%. The sample consisted of 50.4% women and had a mean age of 47.9 years. The sample was reasonable nationally representative, although some sociodemographic groups were somewhat underrepresented.
Despite the COVID-19 restrictions, we were able to build a large and comprehensive dataset of good quality, permitting us to investigate the latest trends in mental health status, various new topics related to mental health, and the extent to which the pandemic has had an effect on the population\'s mental health.
摘要：
目的：NEMESIS-3（荷兰心理健康调查和发病率研究-3）是一项针对荷兰普通人群的精神病流行病学队列研究，该研究复制并扩展了1996-1999年和2007-2018年进行的两项NEMESIS研究。NEMESIS-3的主要目的是提供有关患病率的最新信息，发病率,精神障碍的过程和后果，他们的风险指标，并研究相关的时间趋势。本文概述了NEMESIS-3的目标和方法，特别是最近完成的第一波，并描述样本特征。
方法：NEMESIS-3基于多级，对18-75岁的个体进行分层随机抽样。面对面的采访是由笔记本电脑协助进行的，并在受访者的家中进行。略微修改的综合国际诊断访谈（CIDI）3.0版用于评估精神障碍IV（DSM-IV）和DSM-5精神障碍的诊断和统计手册。计划在基线后三年和六年进行两次随访。
结果：在第一波中，从2019年11月至2022年3月，6194人接受了采访：在COVID-19大流行之前有1576名受访者，在COVID-19大流行期间有4618名受访者。平均访谈时间为91分钟，应答率为54.6%。该样本由50.4%的女性组成，平均年龄为47.9岁。样本具有合理的全国代表性，尽管一些社会人口群体的代表性有些不足。
结论：尽管有COVID-19的限制，我们能够建立一个高质量的大型综合数据集，允许我们调查心理健康状况的最新趋势，与心理健康相关的各种新话题，以及大流行对人口心理健康的影响程度。
方法：NEMESIS-3基于多级，
结果：在第一波中，
结论：尽管有COVID-19的限制，
