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Abstract：
UNASSIGNED: Urinary tract infections (UTIs) have a significant impact on patient\'s quality of life and society. Antibiotic therapy is the primary approach for the management of UTIs; however, it has major limits in the prevention of recurrent UTIs (rUTIs), also increasing the risk of development of multidrug-resistant micro-organisms.
UNASSIGNED: The aim of this paper is to discuss the European Association of Urology guidelines for the management of UTIs/rUTIs, the level of adherence to these recommendations, and the available evidence on the use of glycosaminoglycans (GAGs) as a possible alternative treatment to prevent rUTIs.
UNASSIGNED: This narrative review and expert meeting report is based on a literature search concerning the currently available UTI guidelines, the results of a survey administered to 227 urologists, and the opinion of an expert panel in the field of UTIs.
UNASSIGNED: Results obtained from the literature search showed that adherence to guidelines is not optimal. The survey demonstrated that antibiotics remain one of the treatments of UTIs. However, most of the urologists are aware of the problem caused by the resistance to antibiotics and prefer alternative methods for the prophylaxis of UTIs. Considering the alternative methods, the authors concluded that GAG therapy is highly effective in preventing rUTIs.
UNASSIGNED: Adherence to the international guidelines is important to align the clinical practice and avoid the spreading of antibiotic resistance. The survey outlines that the misuse and overuse of antibiotics are major problems; an analysis of clinical evidence confirms that GAG therapy is a valuable therapeutic approach to prevent the recurrence of episodes of UTIs and to limit the onset of antibiotic resistance.
UNASSIGNED: Although antibiotic therapy is primarily used for the management of urinary tract infections (UTIs), misuse and overuse of antibiotics are of concern. Adherence to the international guidelines is important to prevent the spreading of antibiotic resistance. Clinical evidence confirms that the use of glycosaminoglycans is a valuable therapeutic approach to prevent UTI recurrence and limit the onset of antibiotic resistance.
UNASSIGNED: The aim of this paper is to discuss the European Association of Urology guidelines for the management of UTIs/rUTIs, the level of adherence to these recommendations, and the available evidence on the use of glycosaminoglycans (GAGs) as a possible alternative treatment to prevent rUTIs.
UNASSIGNED: This narrative review and expert meeting report is based on a literature search concerning the currently available UTI guidelines, the results of a survey administered to 227 urologists, and the opinion of an expert panel in the field of UTIs.
UNASSIGNED: Results obtained from the literature search showed that adherence to guidelines is not optimal. The survey demonstrated that antibiotics remain one of the treatments of UTIs. However, most of the urologists are aware of the problem caused by the resistance to antibiotics and prefer alternative methods for the prophylaxis of UTIs. Considering the alternative methods, the authors concluded that GAG therapy is highly effective in preventing rUTIs.
UNASSIGNED: Adherence to the international guidelines is important to align the clinical practice and avoid the spreading of antibiotic resistance. The survey outlines that the misuse and overuse of antibiotics are major problems; an analysis of clinical evidence confirms that GAG therapy is a valuable therapeutic approach to prevent the recurrence of episodes of UTIs and to limit the onset of antibiotic resistance.
UNASSIGNED: Although antibiotic therapy is primarily used for the management of urinary tract infections (UTIs), misuse and overuse of antibiotics are of concern. Adherence to the international guidelines is important to prevent the spreading of antibiotic resistance. Clinical evidence confirms that the use of glycosaminoglycans is a valuable therapeutic approach to prevent UTI recurrence and limit the onset of antibiotic resistance.
摘要：
UASSIGNED：尿路感染（UTIs）对患者的生活质量和社会质量有重大影响。抗生素治疗是尿路感染管理的主要方法;然而，它在预防复发性尿路感染(rUTIs)方面有很大的局限性，也增加了开发耐多药微生物的风险。
UASSIGNED：本文的目的是讨论欧洲泌尿外科协会关于UTI/rUTI管理的指南，遵守这些建议的程度，以及使用糖胺聚糖（GAG）作为预防rUTI的可能替代疗法的现有证据。
UASSIGNED：本叙述性审查和专家会议报告基于有关当前可用的UTI指南的文献检索，对227名泌尿科医师进行的调查结果，以及UTI领域专家小组的意见。
UNASSIGNED：从文献检索中获得的结果表明，遵守指南不是最佳的。调查表明，抗生素仍然是UTI的治疗方法之一。然而,大多数泌尿科医师都意识到由抗生素耐药性引起的问题,因此更喜欢预防尿路感染的替代方法.考虑到替代方法，作者得出结论,GAG治疗在预防rUTI方面非常有效.
UASSIGNED：遵守国际指南对于协调临床实践和避免抗生素耐药性的传播非常重要。该调查概述了滥用和过度使用抗生素是主要问题；对临床证据的分析证实，GAG治疗是预防UTI复发和限制抗生素耐药性发生的有价值的治疗方法。
未经批准：尽管抗生素治疗主要用于尿路感染（UTI）的治疗，滥用和过度使用抗生素令人担忧。遵守国际指南对于防止抗生素耐药性的传播很重要。临床证据证实,使用糖胺聚糖是预防UTI复发和限制抗生素耐药性发生的有价值的治疗方法。
UASSIGNED：本文的目的是讨论欧洲泌尿外科协会关于UTI/rUTI管理的指南，遵守这些建议的程度，以及使用糖胺聚糖（GAG）作为预防rUTI的可能替代疗法的现有证据。
UASSIGNED：本叙述性审查和专家会议报告基于有关当前可用的UTI指南的文献检索，对227名泌尿科医师进行的调查结果，以及UTI领域专家小组的意见。
UNASSIGNED：从文献检索中获得的结果表明，遵守指南不是最佳的。调查表明，抗生素仍然是UTI的治疗方法之一。然而,大多数泌尿科医师都意识到由抗生素耐药性引起的问题,因此更喜欢预防尿路感染的替代方法.考虑到替代方法，作者得出结论,GAG治疗在预防rUTI方面非常有效.
UASSIGNED：遵守国际指南对于协调临床实践和避免抗生素耐药性的传播非常重要。该调查概述了滥用和过度使用抗生素是主要问题；对临床证据的分析证实，GAG治疗是预防UTI复发和限制抗生素耐药性发生的有价值的治疗方法。
未经批准：尽管抗生素治疗主要用于尿路感染（UTI）的治疗，滥用和过度使用抗生素令人担忧。遵守国际指南对于防止抗生素耐药性的传播很重要。临床证据证实,使用糖胺聚糖是预防UTI复发和限制抗生素耐药性发生的有价值的治疗方法。
