PDF(Pubmed)
Abstract：
Total pancreatectomy with islet autotransplantation (TPIAT) is a surgical procedure undertaken in some patients with severe pain or disability from recurrent acute and chronic pancreatitis (CP). TPIAT provides a rare opportunity to study human pancreas tissue from patients affected with pancreatitis, and particularly from patients with genetic forms of pancreatitis. Research to date suggests distinct histopathology and potentially differential pathophysiology of distinct etiologies of CP. Histopathology specimens have helped better define the success and limitations of clinical diagnostic imaging tools, such as magnetic retrograde cholangiopancreatography and endoscopic ultrasound.
摘要：
胰岛自体移植全胰腺切除术（TPIAT）是一些因复发性急性和慢性胰腺炎（CP）而严重疼痛或残疾的患者进行的外科手术。TPIAT为研究胰腺炎患者的胰腺组织提供了难得的机会，特别是患有遗传性胰腺炎的患者。迄今为止的研究表明CP的不同病因的不同组织病理学和潜在差异病理生理学。组织病理学标本有助于更好地定义临床诊断成像工具的成功和局限性。如磁性逆行胰胆管造影术和超声内镜。
