关键词: Autoimmune Bipolar disorder Case report Neuropsychiatry Sjogren syndrome Autoimmune Bipolar disorder Case report Neuropsychiatry Sjogren syndrome

来  源:   DOI:10.1016/j.amsu.2022.104243   PDF(Pubmed)

Abstract:
UNASSIGNED: Sjögren\'s syndrome is an autoimmune disease affecting exocrine glands and other organs. At the onset of the disease and during its course, it most commonly manifests as neuropsychiatric symptoms, most frequently, depression and anxiety. However, the association with bipolar disorder seems rare and not frequently documented.
UNASSIGNED: Our case report presents a 43-year-old male complaining from neuropsychiatric symptoms including but not limited to periods of elevated mood, increased energy, headaches. Examination revealed xerophthalmia and xerostomia, thus Sjogren\'s Syndrome was diagnosed. A psychiatric consultation further diagnosed the patient with Bipolar Disorder. Successful treatment consisted of Carbamazepine and Azathioprine.
UNASSIGNED: People with immunological diseases like Sjogren\'s Syndrome have a higher chance of developing Bipolar Disorder with an unclear etiology. Clinical symptoms, MRI findings, and cerebral fluid analysis can lead to a proper diagnosis. Treatments include usual treatment for Sjogren\'s such as corticosteroids and immunosuppressants, in the addition of mood stabilizers for Bipolar.
UNASSIGNED: Psychiatry assessments should be done systematically in patients with autoimmune diseases to avoid delays in diagnosis and to make better treatment decisions.
摘要:
未经证实:干燥综合征是一种影响外分泌腺和其他器官的自身免疫性疾病。在疾病发作及其过程中,通常表现为神经精神症状,最常见的是,抑郁和焦虑。然而,与双相情感障碍的关联似乎很少见,也没有经常记录。
未经评估:我们的病例报告显示,一名43岁的男性主诉神经精神症状,包括但不限于情绪升高,增加能量,头痛。检查显示干眼症和口干症,因此干燥综合征被诊断出来。精神病会诊进一步诊断为双相情感障碍患者。成功的治疗包括卡马西平和硫唑嘌呤。
UNASSIGNED:患有免疫疾病如干燥综合征的人发生双相情感障碍的几率更高,病因不明。临床症状,MRI检查结果,和脑液分析可以导致正确的诊断。治疗包括干燥综合征的常规治疗,如皮质类固醇和免疫抑制剂,在添加情绪稳定剂的双极。
UNASSIGNED:应该对自身免疫性疾病患者进行系统的精神病学评估,以避免延误诊断并做出更好的治疗决定。
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