An 81-year-old male presented with progressive dyspnea. Computed tomography (CT) of the chest showed a 6.2 × 5.3 cm soft tissue mass in the anterior mediastinum. Further imaging with CT angiogram showed a stalk-like connection to the pericardium. A biopsy of the mass showed spindle cells positive for BCL-2, CD34, and STAT 6, indicative of a solitary fibrous tumor. A surveillance approach was adopted for the patient.
Primary pericardial tumors are exceedingly rare, with a prevalence rate of 0.001%-0.007%. Diagnosing a SFT requires a positive CD34 and BCL-2 marker. The current recommendation is resection of localized disease which has been documented to be curative in cases of benign disease however our patient was put on surveillance.
一名81岁男性出现进行性呼吸困难。胸部计算机断层扫描(CT)显示前纵隔有6.2×5.3cm的软组织肿块。CT血管造影的进一步成像显示与心包的茎状连接。肿块的活检显示梭形细胞对BCL-2,CD34和STAT6呈阳性,表明孤立性纤维瘤。对患者采取监测方法。
原发性心包肿瘤极为罕见,患病率为0.001%-0.007%。诊断SFT需要阳性CD34和BCL-2标志物。当前的建议是切除局部疾病,据记载,在良性疾病的情况下可以治愈,但对我们的患者进行了监视。