Abstract：
Cardiac undifferentiated pleomorphic sarcoma (UPS) associated with fever and inflammatory response is an extremely rare condition. Herein, we report a rare case of cardiac UPS with unusual clinical presentation and inflammatory response. A 67-year-old male complaining of progressive dyspnea and intermittent fever of unknown cause was referred to our hospital for surgical resection of a left atrial mass. Laboratory analysis showed leukocytosis (26 × 103/μL) and high C-reactive protein (CRP) levels (155.4 mg/L). Hemoculture tests and urine analysis were negative for infection. A contrast chest computed tomography revealed a mass measuring 5.5 × 4.5 cm, occupying the left atrium cavity. The patient underwent surgical excision of the mass, however, surgical margin of the resected tumor could not be evaluated, due to the multifragmented nature of the resection specimen. Postoperative CRP and leukocyte levels normalized, highlighting the relationship between the tumor and the inflammatory status. Early diagnosis is crucial for a proper management and favorable outcome, enabling patients to undergo chemotherapy and achieve complete surgical resection.
摘要：
与发烧和炎症反应相关的心脏未分化多形性肉瘤（UPS）是一种极为罕见的疾病。在这里，我们报告了一例罕见的心脏UPS病例,临床表现和炎症反应异常.一名67岁的男性抱怨进行性呼吸困难和不明原因的间歇性发烧，被转诊到我们医院进行左心房肿块的手术切除。实验室分析显示白细胞增多（26×103/μL）和高C反应蛋白（CRP）水平（155.4mg/L）。血培养试验和尿液分析均为感染阴性。对比胸部计算机断层扫描显示肿块大小为5.5×4.5厘米，占据左心房腔。病人接受了肿块的手术切除,然而,无法评估切除肿瘤的手术切缘，由于切除标本的多片性质。术后CRP和白细胞水平恢复正常，突出肿瘤和炎症状态之间的关系。早期诊断对于正确的管理和良好的结果至关重要，使患者能够接受化疗并实现完整的手术切除。
