Abstract：
Cancer immunotherapy has received more and more attention from cancer researchers over the past few decades. Various methods such as cell therapy, immune checkpoint blockers, and cancer vaccines alone or in combination therapies have achieved relatively satisfactory results in cancer therapy. Among these immunotherapy-based methods, cancer vaccines alone have not yet had the necessary efficacy in the clinic. Therefore, nanomaterials have increased the efficacy and ef-fectiveness of cancer vaccines by increasing their half-life and durability, promoting tumor mi-croenvironment (TME) reprogramming, and enhancing their anti-tumor immunity with minimal toxicity. In this review, according to the latest studies, the structure and different types of nanovaccines, the mechanisms of these vaccines in cancer treatment, as well as the advantages and disadvantages of these nanovaccines are discussed.
摘要：
在过去的几十年中，癌症免疫疗法越来越受到癌症研究人员的关注。各种方法，如细胞疗法，免疫检查点阻断剂，和癌症疫苗单独或联合治疗在癌症治疗中取得了相对令人满意的结果。在这些基于免疫疗法的方法中，单独的癌症疫苗在临床上还没有必要的功效。因此,纳米材料通过增加其半衰期和耐久性来提高癌症疫苗的功效和功效，促进肿瘤微环境（TME）重编程，并以最小的毒性增强其抗肿瘤免疫力。在这次审查中,根据最新的研究,纳米疫苗的结构和不同类型，这些疫苗在癌症治疗中的作用机制，以及这些纳米疫苗的优缺点进行了讨论。
