Abstract：
While parafoveal word processing plays an important role in natural reading, the underlying neural mechanism remains unclear. The present study investigated the neural basis of parafoveal processing during Chinese word reading with the co-registration of eye-tracking and functional magnetic resonance imaging (fMRI) using fixation-related fMRI analysis. In the gaze-contingent boundary paradigm, preview conditions (words that are identical, orthographically similar, and unrelated to target words), pre-target word frequency and target word frequency were manipulated. When fixating the pre-target word, the identical preview condition elicited lower brain activation in the left fusiform gyrus relative to unrelated and orthographically similar preview conditions and there were significant interactions of preview condition and pre-target word frequency on brain activation of the left middle frontal gyrus, left fusiform gyrus and supplementary motor area. When fixating the target word, there was a significant main effect of preview condition on brain activation of the right fusiform gyrus and a significant interaction of preview condition and pre-target word frequency on brain activation of the left middle frontal gyrus. These results suggest that fixation-related brain activation provides immediate measures and new perspectives to understand the mechanism of parafoveal processing in self-paced reading.
摘要：
虽然半心字处理在自然阅读中起着重要的作用，潜在的神经机制仍不清楚.本研究使用与固定相关的fMRI分析，通过眼睛追踪和功能磁共振成像（fMRI）的配准，研究了汉语单词阅读过程中的旁凹处理的神经基础。在凝视或有边界范式中，预览条件（相同的单词，正交相似，并且与目标单词无关)，操纵预目标词频和目标词频。当固定前目标单词时，相对于无关和正形相似的预览条件，相同的预览条件在左旋回中引起较低的大脑激活，并且预览条件和目标前单词频率对左额中回的大脑激活存在显着相互作用，左梭状回和辅助运动区。当固定目标单词时，预览条件对右梭状回脑激活有显着的主要影响，预览条件和目标前词频对左额中回脑激活有显着的交互作用。这些结果表明，与固定相关的大脑激活提供了立即的措施和新的观点，以了解自定进度阅读中的旁凹加工机制。
